OBJECTIVE There has been little investigation of early trauma in bipolar disorder despite evidence that stress impacts on the course of this illness. We aimed to compare the rates of childhood trauma in adults with bipolar disorder to a healthy control group, and to investigate the impact of childhood trauma on the clinical course of bipolar disorder. METHODS Retrospective assessment of child...

OBJECTIVES Emotion regulation deficits are a core feature of bipolar disorder. However, their potential neurobiological underpinnings and existence beyond bipolar I disorder remain unexplored. Our main goal was to investigate whether both individuals with bipolar I and bipolar II disorder show deficits in emotion regulation during an attention control task, and to explore the neurophysiological...

INTRODUCTION Several studies have been carried out regarding the possible overlap between Bipolar Disorder and borderline personality disorder. Up to now, it is not possible to provide a definitive picture. In fact, there is currently significant debate about the relationship between Borderline Personality Disorder and Bipolar Disorder. METHODS MEDLINE searches were performed to identify the ...

objective: bipolar disorder is a severe mental disorder, and its prevalence is around 1% to 2%. despite a vast literature around bipolar disorder, the reasons of its nonadherence and rehospitalization is still obscure. several symptoms of bipolar disorder include changes in activity level, cognitive abilities, speech, and vegetative functions, such as sleep, sexual activity, as well as aggressi...

objective: bipolar disorder is strongly associated with suicidal ideations, attempts and commissions. although several studies have been conducted on suicide risk factors in patients with bipolar disorder worldwide, a comprehensive study has not been reported from iran. methods: patients with bipolar disorder type i, hospitalized in iran hospital of psychiatry since may 2008 to august 2011 were...

background: bipolar mood disorder type 1 is one of the most serious psychiatric disorders. we aimed to assess the efficacy of a short-term family–focused treatment for patients with bipolar mood disorder type 1 in a one-year follow-up period.   methods: sixty patients with bipolar mood disorder and acute mania episodes who referred to ibn-e-sina psychiatric hospital in mashhad were recruited. h...

BACKGROUND Hypersomnia in inter-episode bipolar disorder has been minimally researched. The current study sought to document the prevalence of hypersomnia in a sample of inter-episode patients with bipolar disorder and to examine the relationship between hypersomnia and future bipolar depressive symptoms. METHODS A total of 56 individuals with bipolar disorder (51 type I+5 type II) who were c...