background: the most common clinical indication of aminoglycosides (ag) is the treatment of serious gram?negative infections.the aim of this study was to evaluate plausible effects of atorvastatin on the biomarkers of acute kidney injury (aki) in patients receiving amikacin. materials and methods: in this double?blinded randomized clinical trial, fifty patients (25 in each group) receiving amik...

the aim of this study was to investigate the effects of administering antioxidants, including vitamin c and chitosan on oxidative stress markers in muscle as edible tissues of cyprinus carpio exposed to cadmium chloride. in this experiment, by exposing to 0.2 mg/l cadmium chloride for 21 days, fish were fed a normal diet, diet containing chitosan (1000 mg/kg diet), vitamin c (1000 mg/kg diet) o...

conclusions expression of hmgb1 and c-iap2 proteins was associated with hcc development and progression, and the expression of hmgb1 and c-iap2 proteins in hcc were significantly associated with each other. additionally, these proteins may show promise as biomarkers to predict hcc progression. background hepatocellular carcinoma (hcc) is one of the most important health problems in china. objec...

this study aimed to assess whether the triethylenetetramine (teta) is impressed the plasma level of homocysteine (hcy), total sialic acid (tsa) and cardiac troponin i (ctni) as cardiovascular diseases risk factors, cystatin c (cys c) and glucose along with histopathologic changes in alloxan induced diabetes mellitus in rabbit. twenty number new zealand white rabbits were assigned for this study...

biological marker is a term used in many scientific fields and was introduced as a measurable element or a clinical indicator in the abnormal biological processes, pathological condition, or pharmacological intervention. science citation index expanded (sci-e) from database of web of science (wos) was used to extract all publication indexed as a topic of “ biomarkers ” during a period of eleven...

Asthma is a heterogeneous disease, in which asthmatic patients present with different clinical phenotypes, variable endotypes, and different response to asthma medicines. Thus, we are faced with an asthma paradox; asthma is diagnosed subjectively by clinical history and treated with biologically active drugs. To solve this paradox, we need objective airway biomarkers to tailor the proper medica...

context primary liver cancer is one of the most common and deadly malignant neoplasms worldwide. the incidence and mortality rates for hepatocellular carcinoma (hcc) are virtually identical, reflecting the poor overall survival of patients with this kind of tumor. effective therapies mostly achieved if the hcc diagnosis is made at early stages of the tumor. surveillance tests include serologic ...