biological activity

Ahmad Fazeli, Ali Mohammadi, Hosein Rastegar, Mahmoud Alebouyeh, Mohammad Reza Fazeli, Mohammad Reza Khoshayand, Sameereh Hashemi-Najafabadi, Tahereh Babaee,

Recombinant plasminogen activator (reteplase) is a third generation thrombolytic agent which has been used on coronary artery thrombosis and acute myocardial infarction. Clot lysis assay is usually considered as a unique method to evaluate biological activity of reteplase. In this study biological activity of reteplase was determined by APTT (activated partial thromboplastin time) lysis method....

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synthesis and cytotoxicity study of new cyclopenta[b] quinoline-1,8-dione derivatives

Journal: :iranian journal of pharmaceutical research 0

ramin miri medicinal and natural products chemistry research center, shiraz university of medical sciences. shiraz, iran. pharmaceutical sciences research center, tehran university of medical sciences. tehran, 14174, iran omidreza firuzi medicinal and natural products chemistry research center, shiraz university of medical sciences. shiraz, iran. payam peymani medicinal and natural products chemistry research center, shiraz university of medical sciences. shiraz, iran. zohreh nazarian pharmaceutical sciences research center, tehran university of medical sciences. tehran, 14174, iran. department of medicinal chemistry, faculty of pharmacy, tehran university of medical sciences, tehran, iran. abbas shafiee pharmaceutical sciences research center, tehran university of medical sciences. tehran, 14174, iran. department of medicinal chemistry, faculty of pharmacy, tehran university of medical sciences, tehran, iran.

dna intercalators belong to aromatic heterocyclic compounds interacting reversibly with dna. these compounds have been used extremely as cytotoxic agents against cancer. in this study, the synthesis and biological activity of some novel derivatives of cyclopenta [b] quinoline-1, 8-dione as new intercalating agent were investigated. twenty novel derivatives of cyclopenta [b] quinoline-1, 8-dione...

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Determination of Biological Activity of Recombinant Reteplase Using Clot Lysis Time and Activated Partial Thromboplastin Time (APTT) Lysis Methods: A Comparative Study

Journal: The Iranian Journal of Pharmaceutical Research 2018

Ahmad Fazeli, Ali Mohammadi, Hosein Rastegar, Mahmoud Alebouyeh, Mohammad Reza Fazeli, Mohammad Reza Khoshayand, Sameereh Hashemi-Najafabadi, Tahereh Babaee,

Recombinant plasminogen activator (reteplase) is a third generation thrombolytic agent which has been used on coronary artery thrombosis and acute myocardial infarction. Clot lysis assay is usually considered as a unique method to evaluate biological activity of reteplase. In this study biological activity of reteplase was determined by APTT (activated partial thromboplastin time) lysis method....

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antimicrobial peptides (amps)

Journal: :novelty in biomedicine 0

mehrzad sadredinamin department of microbiology, school of medicine, shahid beheshti university of medical sciences,p. o. box 1985717443, tehran, iran. faramarz mehrnejad department of life science engineering, faculty of newsciences & technologies, university of tehran,p.o. box 14395-1561, tehran, iran. peyman hosseini department of microbiology, qazvin university of medical sciences,p.o.box: 34185-754 qazvin, iran. farahnoosh doustdar 1- department of microbiology, school of medicine, shahid beheshti university of medical sciences,p. o. box 1985717443, tehran, iran.

antimicrobial peptides (amps) are extensive group of molecules that produced by variety tissues of invertebrate, plants, and animal species which play an important role in their immunity response. amps have different classifications such as; biosynthetic machines, biological sources, biological functions, molecular properties, covalent bonding patterns, three dimensional structures, and molecul...

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