In drug therapy, most therapeutic drugs are of low molecular weight and could freely diffuse in the biological milieu depending on the administration route applied. The main reason for the development of polymeric drug carriers is to obtain desired effects such as sustained therapy, local and controlled release, prolonged activity and reduction of side effects. Alternatively, polymeric carriers...

The behavior of tethered polymers on gel/gel adhesion is studied with the single-chain mean-field ~SCMF! theory. It is shown that the gel surface structure, the gel/gel adhesion strength, the equilibrium gel/gel distance, and the detailed interface structures can be tailored by specifically designed tethered layers on gel surfaces. The SCMF theory allows to study the effect of various variables...

high purity lead titanate nanopowders in tetragonal form have been successfully prepared bycitric acid gel method using lead nitrate and tetra-n-butyl titanate as pb and ti sourcesrespectively and citric acid as complexing reagent. the precursors were calcined at varioustemperatures ranging from 450 °c to 600 °c for 2 h. fourier transform infraredspectroscopy (ft-ir), x-ray diffraction (xrd) an...

introduction: multiple fields and presence of heterogeneities create complex dose distributions that need three dimensional dosimetry. in this work, we investigated mr-based magic gel dosimetry as a three-dimensional dosimetry technique to measure the delivered dose to bladder and rectum in prostate radiation therapy. materials and methods: a heterogeneous slab phantom including bones was made....

Background: Topical retinoid based combinations are recommended to enhance the outcome of acne treatment. Adapalene-benzoyl peroxide (BPO) combination gel was approved in 2009 for acne treatment. The aim of this study was to evaluate the efficacy and tolerability of adapalene 0.1%-benzoyl peroxide 2.5% combination gel compared to adapalene 0.1% gel monotherapy and benzoyl peroxide 2.5% gel mono...