نتایج جستجو برای: bioavailable fraction
تعداد نتایج: 154635 فیلتر نتایج به سال:
Total 25(OH)D levels were determined to assess bone health in elderly populations; however, the bioavailability of 25(OH)D is regulated by the albumin and vitamin D binding protein (DBP) levels and DBP variations. Whether bioavailable 25(OH)D level is a superior biomarker for vitamin D than total 25(OH)D level regarding the BMD and the bone metabolism were not yet fully understood. With a commu...
Ingestion of soil represents one the critical exposure pathways in human health risk assessment (HHRA) framework at sites contaminated by inorganic species, especially for residential scenarios. HHRA is typically carried out through starting from so-called “total concentration”, which estimated fraction species extracted using standardized approaches, i.e., microwave acid extraction. Due to mil...
The human serum Sex Hormone-Binding Globulin (SHBG) plays an important role in breast cancer pathophysiology and risk definition, since it regulates the bioavailable fraction of circulating estradiol. We here summarize data reported over the years concerning the involvement of SHBG and SHBG polymorphisms in the definition of breast cancer risk. We also report what is known about the direct acti...
BACKGROUND Experimental studies demonstrate beneficial immunological and hemodynamic effects of estradiol in animal models of sepsis. This raises the question whether estradiol contributes to sex differences in the incidence and outcomes of sepsis in humans. Yet, total estradiol levels are elevated in sepsis patients, particularly nonsurvivors. Bioavailable estradiol concentrations have not pre...
Atmospheric inputs of iron to the open ocean are hypothesized to modulate ocean biogeochemistry. This review presents an integration of available observations of atmospheric iron and iron deposition, and also covers bioavailable iron distributions. Methods for estimating temporal variability in ocean deposition over the recent past are reviewed. Desert dust iron is estimated to represent 95% of...
The role of endogenous sex hormones in many diseases makes understanding factors that influence levels of these hormones increasingly important. This study examined age-associated variations in total and bioavailable testosterone and estradiol levels among community-dwelling Caucasian men in Rancho Bernardo, California. Plasma samples obtained from 810 men aged 24-90 years in 1984-1987 were ana...
The study aims at investigating chemical speciation, bioavailability and risk assessment of some selected metals in soils around refined petroleum depot using the concentrations as variables to ascertain impacts activities within depot. Surface-soils (0–15 cm) were collected from premises Pipelines Product Marketing Company, Ibadan, Nigeria, while control samples 200 m away location. Electrical...
Low Fe bioavailability has been suggested as a potential constraint on primary production in the Great Lakes. Here we report on the use of a cyanobacterial bioreporter to assess available Fe in Lake Erie during summer and fall field seasons in 2001–02. Bioreporter luminescence was derived from a luciferase reporter controlled by iron-responsive promoter element isiAB. Filtered (< 0.2 μm) water ...
This study assessed copper and zinc distribution in the surface layer of sediment and rhizome tissue within the saturated surface vertical flow constructed wetland of CSBP Ltd, a fertiliser and chemical manufacturer located in Western Australia. Sediment and Schoenoplectus validus rhizome samples were collected at various distances from the inlet pipe while water samples are routinely collected...
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