Rheumatoid arthritis is an inflammatory disease, and pyroptosis a form of death associated with response. Pyroptosis, which occurs in synovial osteoblastic cells, can exacerbate the development rheumatoid arthritis. The inhibition these cells can, therefore, clearly be used as therapeutic strategy against Here, we have summarized current status progress treatment by targeting cellular pyroptosi...

Supramolecular nanostructures covered with bioactive functional molecules have been actively explored as promising materials in the field of biotechnology. Recent advances in nano-sized chemistry have made it possible to fabricate various kinds of nanostructures with tailor-made nanostructural properties. This, combined with appropriate bioactive functionalization, has led to the successful uti...

The five membered heterocycles isoxazolines are considered as important class of compounds in bioorganic and medicinal chemistry. They were treated as useful intermediates for transforming to large number of bioactive molecules. These classes of compounds were known to have varied biological activities. In this review, critical discussion has been made on synthetic methodologies developed, util...