objective: osseous defects around dental implants are often seen when implants are placed in areas with inadequate alveolar bone, or around failing implants. bone regeneration in these areas using bone grafts or its substitutes may improve dental implants prognosis. the aim of this study was to prepare and characterize the bioactive glass nanopowder and development of its coating for treatment ...

Marine Streptomyces are prolific producers of majority of bioactive secondary metabolites which are used in pharmaceutical industry as effective drugs against life threatening diseases. The cytotoxic activity of the pure compound 1, 2- benzene dicarboxylic acid, mono 2- ethylhexyl ester (DMEHE) from marine derived actinomycete Streptomyces sp. VITSJK8 was investigated against mouse embryonic fi...

Inclusion bodies produced in Escherichia coli are composed of densely packed denatured protein molecules in the form of particles. Refolding of inclusion body proteins into bioactive forms is cumbersome, results in poor recovery and accounts for the major cost in production of recombinant proteins from E. coli. With new information available on the structure and function of protein aggregates i...

Apis cerana is a honey bee species with cavity hive known as the eastern bee. Honey hives have Indigenous bacteria that antimicrobial potential. are free can synthesize nitrogen compounds, sugars, and other bioactive substances. This study aims to isolate, identify test antibacterial of isolate against gram-positive Staphylococus aureus gram-negative Escherichia coli. used descriptive research ...

Bioactive-directed fractionation of n-butanol extract from fresh fruits of Randia siamensis led to isolate of 4 new pseudoginsenoside compounds: pseudoginsenosides-RT2, -RT3, RT4 and -RT5, together with 7 known compounds: tyramine, pseudoginsenosides-RT1 methyl ester, pseudoginsenosides-RT1, pseudoginsenoside-RP1, kaempferol-3-O-β-D-xylose(1-2)-βgalactose, kaempferol-3-O-β-D-galactose, and 5-O...

High-speed counter-current chromatography (HSCCC) was applied to isolate and purify bioactive compounds in the essential oil of the rhizomes of Curcuma wenyujin. Two sesquiterpenes germacrone and curdione were successfully isolated and purified using two-phase solvent system composed of petroleum ether-ethanol-diethyl ether-water (5/4/0.5/1, v/v) in tail to head elution mode. 62 mg of germacron...

In higher plants, long-chain fatty acid hydroperoxides are intermediates in the synthesis of a diverse group of bioactive compounds. We used the reverse trascriptase-polymerase chain reaction to isolate a gene responsible for the oxidization of fatty acids from Petunia hybrida. A P450 cDNA not isolated earlier, CYP92B1, contained an open reading frame predicted to encode a polypeptide consistin...

Luobuma (Apocynum venetum L. (AVL)) is a popular beverage in Asia and has been reportedly to be associated with the bioactivities such as cardiotonic, diuretic, antioxidative, and antihypertensive. However, its biofunction as chemoprevention activity is seldom addressed. Herein, we aimed to characterize the anti-androgen-insensitive-prostate-cancer (anti-AIPC) bioactive compounds of Luobuma, an...

Objective: This piece of work aims to determine the antagonistic potential of Aspergillus melleus MP3 fungi from marine sponge. Methods: Marine sponge extract was used to isolate fungi on selective medium and molecular identification was performed using ITS sequencing. Fungal mycelium was extracted with solvents of varying polarity and their antibacterial activity was checked against various hu...