www.icjournal.org Human Anaplasmosis in Acute Febrile Patients during Scrub Typhus Season in Korea Myung-Jo You, Won-Il Kim, Ho-Seong Cho, Gee-Wook Shin, Jeong-Hwan Hwang, and Chang-Seop Lee Bio-safety Research Institute and College of Veterinary Medicine; Department of Internal Medicine, Chonbuk National University; Research Institute of Clinical Medicine of Chonbuk National University, Chonbu...

deveLopment oF a wide-view visuaL presentation system and estimating human primary visuaL corticaL magniFication by using Fmri For traFFic saFety Jinglong WU Professor and Lab. head, Bio-Measurement engineering Laboratory Division of Industrial Innovation Sciences, The Graduate School of Natural Science and Technology, Okayama University, Okayama, Japan Fengzhe JIN Graduate School of engineerin...

Introduction Application on industrial production of biomolecules Human therapeutics from recombinant DNA technology Success story of Insulin Host used for therapeutic production Safety of the recombinant biomolecules Human monoclonal antibody Application in Agriculture Development of stress tolerant plant Development of plant having improved yield Transgenic plant as a source of bio pharmaceut...

Low-frequency (LF) ultrasound (20-100 kHz) has a diverse set of industrial and medical applications. In fact, high power industrial applications of ultrasound mainly occupy this frequency range. This range is also used for various therapeutic medical applications including sonophoresis (ultrasonic transdermal drug delivery), dentistry, eye surgery, body contouring, the breaking of kidney stones...

(89)Zr-based imaging agents hold great promise as novel radio-tracers in nuclear medicine. However, insufficient stability of currently used radiometal complexes in vivo is a safety concern for clinical applications. We herein report the first octadentate bifunctional chelating agent for the development of (89)Zr-labelled (bio)conjugates with improved stability.

The Predictive Safety Testing Consortium (PSTC) is one of nine consortia comprising the Critical Path Institute (C-Path), a non-profit organisation launched in 2005 and dedicated to playing the role of a catalyst in the development of new approaches that advance medical innovation and regulatory science. C-Path achieves this by leading teams that share data, knowledge and expertise resulting in...

BACKGROUND To compare both safety and efficacy of a novel intra-articular viscosupplement made of intermediate molecular weight (MW) hyaluronic acid (HA) mixed with high concentration of mannitol with a marketed high MW HA, in patients with knee osteoarthritis (OA). METHODS Patients with symptomatic knee OA, with radiological OARSI grades 1 to 3, were enrolled in a controlled, double-blind, p...

development of aseptic techniques. Pasteur’s work in 1861 on spoilage of foodstuffs by microorganisms, and the subsequent development of pasteurization, laid the foundations for the modern principles of aseptic technique and manufacture. Whether it is employed in hospitals to prevent patient infection, food processing to prolong shelf-life or pharmaceutical manufacturing to ensure product integ...

Bio–nanoscience research encompasses studies on the interactions of nanomaterials with biological structures or what is commonly referred to as biointerface. Fundamental influence nanomaterial properties, including size, shape, composition, and charge, interaction biointerface have been central in bio–nanoscience assess efficacy safety for a range biomedical applications. However, state cells, ...

Food safety in three dimensions refers to the matrix of issues and activities that lead to safe food consumption in today’s world. Starting with the first principle that food should nourish the body and not cause illness, debilitation, or death, a broader concept, “safe food consumption,” is called for. Food safety typically refers to food that is free from harmful, but naturally occurring micr...