نتایج جستجو برای: binding constant

تعداد نتایج: 626466  

Cinnamaldehyde is an important compound of the cinnamon essential oil, and it is responsible for the most of the health benefits of cinnamon. Enriching foods such as milk with cinnamaldehyde can lead to greater utilization of cinnamaldehyde properties. In this study, we investigated the interaction of cinnamaldehyde with bovine alpha-lactalbumin. Analyzing the spectrum of alpha-lactalbumin in t...

Farrokh Gharib Karim Zare, Meysam Shirmohammadi Morteza Keshavar

Spectropholornetrie technique is used to evaluate binding of the vanadium(1U) ion to a water solublecaruc[4] arene molecule in aqueous solution. On the basis of the calculated value formation constant at25rC.we found that the eomplexation of this metal on is very favored towards 25, 26, 27, 2Stetrahydroxy-5, 11, 17, 23-tetnmulphonalic acid-calix[0]areneGaussian 03 package.

Magnesium is an abundant element in the environment. Magnesium ion sensing by fluorescence spectral method is of importance due to the need for the detection of the metal in the human body and the environment. In this paper, we report the Mg2+ ion sensing behavior of the phenylhydrazone derivative of a difluorenylpiperidin-4-one. The preparation method of this compound is simple. The compound s...

Journal: :journal of physical & theoretical chemistry 2006
r. hakimelahi m.a. seyed sadjadi h. aghaie m. aghaie

neutral bidentate n-o type complexe of vo(ii) has been synthesized through condensation of dpenicillamine,(d-h2pen), with bis(acetylacetonate)- oxovanadium(iv),[vo(acac)2], at neutralmedium . the established schiff base(no type) complex was characterized on the basis of ir andmass spectroscopy techniques.besides,d-h2pen binding behavior to[vo(acac)2] has been studiedin thermodynamic viewpoint u...

Journal: :research in pharmaceutical sciences 0

recently, several studies have shown that the metal-fluoroquinolone complexes have more antibacterial and cytotoxic effects in comparison with free fluoroquinolones. these results may introduce new drugs for chemotherapy with fewer side effects. in this work a bidentated zinc (ii) complex with ofloxacin (ozc) was synthesized and cytotoxicity activities and dna binding of the resulted complex wa...

Journal: :journal of physical & theoretical chemistry 2004
h. aghaie m. keshavarz k. zare a.k. bordbar f. gharib

porophyrins and their metal derivatives are strong dna binders with association constant of  to  . some of these compounds have been used for the radiations sensitization therapy of cancer and are targeted to interact with cellular dna. binding of porphyrins to dna changes the expectral and other physic chemical characteristic of porphyrins, the mode of binding can be extracted from inspection ...

2003
S. H. Pomerantz

3,4-Dihydroxy-L-phenylalanine (dopa) has been shown to account for the cofactor activity for tyrosinase contained in extracts of hamster melanoma. Dopa has been identified by several different comparisons with an authentic sample and by conversion to two derivatives. The amount of dopa in the tumor (4 to 8 pg per g) has been estimated by cofactor assay and fluorometry. A Km value for dopa as a ...

ژورنال: ارمغان دانش 2021

Background and aim: Podophyllotoxin is used as one of the main treatments for genital warts. It is a precursor of etoposide and teniposide, which is used in the treatment of various cancers. Despite a large number of cancer studies, the exact mechanism of podophyllotoxin remains unknown. Chemotherapy drugs reduce cancer cells by inducing apoptosis. The regulation of the apoptotic pathway has be...

Journal: :journal of physical & theoretical chemistry 2005
h. aghaie m. keshavarz k. zare m. aghaie a.k. bordbar

in order to shed more light on the effect of peripheral groups of porphyrin core intophysicochemical properties and dna binding behavior of porphyrins, we have chosen toinvestigate solution properties and calf thymus dna binding behavior of meso-tetrakis (4-nbenzyl-pyridyl) porphyrin (tbzpyp) and its mn (iii), co (iii), ni (ii) and cu (ii) complexesderivatives have been studied in thermodynamic...

Journal: :European Journal of Biochemistry 1977

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