Objective: Oxidative stress and antioxidant deficiency play key roles in the pathogenesis of gastrointestinal damage associated with Crohn's disease (CD). Serum bilirubin, uric acid (UA) albumin are non-enzymatic antioxidants that a role oxidative control. In this study, it was aimed to evaluate change serum UA levels due activity.
 Material Method: This study designed as single-center, cr...

INTRODUCTION Increased levels of C-Reactive Protein are found in 30-60% on hemodialysis patients and it is closely associated with the progression of atherosclerosis, cardiovascular morbidity and mortality. Non enzymatic antioxidants are antioxidants which primarily retain potentially dangerous ions of iron and copper in their inactive form and thereby prevent its participation in the productio...

objective(s): titanium dioxide (tio2) nanoparticles (nps) are widely used in commercial food additives and cosmetics worldwide. uptake of these nanoparticulate into humans by different routes and may exhibit potential side effects, lags behind the rapid development of nanotechnology. thus, the present study designed to evaluate the toxic effect of mixed rutile and anatase tio2 nps on serum bioc...

We compared results obtained with the Beckman Creatinine Analyzer (Beckman Instruments, Inc.) to those with the GEMSAEC Centrifugal Analyzer (Electro-Nucleonics, Inc.) and with a manual method for determination of creatinine in serum and urine. Linearity, stability, recovery, and precision were evaluated. Interference from bilirubin, protein, lipemia, uric acid, and hemolysis is negligible, but...

The aim of the work was to assess the influence of some non-enzymatic antioxidants (uric acid, blood urea, bilirubin) on the antioxidant status of rat’s organism during the experimental acute haemorrhagic necrotising pancreatitis. The experiment was carried out on male Wistar rats, body weight 280-320 g, which were divided randomly into control and experimental groups. The control group (n=8) u...

BACKGROUND The role of non-enzymatic antioxidants, such as uric acid, albumin, bilirubin, and α-tocopherol, in lead poisoning remains unclear. Therefore, the aim of the study was to explore the association between occupational exposure to lead and non-enzymatic antioxidant concentrations in serum and plasma. MATERIAL AND METHODS The study population consisted of 278 healthy male employees of ...

the present study aimed to compare the serum level of uric acid in patients with and without heart failure and also to determine the association between uric acid level and clinical status by killip class in patients with stemi. this case-control study was conducted on 50 consecutives as control group and 50 patients with acute heart failure, (20 patients had acute stemi), who documented by bot...

Bilirubin, when bound to human albumin and at concentrations present in normal human plasma, protects albumin-bound linoleic acid from peroxyl radical-induced oxidation in vitro. Initially, albumin-bound bilirubin (Alb-BR) is oxidized at the same rate as peroxyl radicals are formed and biliverdin is produced stoichiometrically as the oxidation product. On an equimolar basis, Alb-BR successfully...

objective: the goal of this study was to assess the utility of serum uric acid in preeclampsia diagnosis and its correlation with some maternal and fetal outcomes. materials and methods: a case-control study was performed on 26 term pregnant women with preeclampsia and 52 normal pregnant women. serum uric acid, platelet count, hematocrit, gestational age, and birth weight of all patients were m...

OBJECTIVE To assess the effect of phototherapy on serum oxidant and antioxidant status in hyperbilirubinemic full-term newborns. METHOD Thirty-four full-term infants from 3 to 10 days of age exposed to phototherapy were studied. The serum antioxidant status was assessed by measuring the total antioxidant capacity (TAC) and individual antioxidant components: vitamin C, uric acid, albumin, thio...