Exposure to beryllium compounds, both by inhalation and skin contact, may result in immune sensitization and chronic beryllium disease. The objective of the present research work was to study the feasibility of removing beryllium compounds from the surfaces of devices made of Be-Cu alloy and to estimate the frequency at which the surfaces had to be rubbed in order to evaluate the likelihood tha...

BACKGROUND Understanding the progression from beryllium exposure (BeE) to chronic beryllium disease (CBD) is essential for optimizing screening and early intervention to prevent CBD. METHODS We developed an analytic markov model of progression to cbd that assigns annual probabilities for progression through three states: from BeE to beryllium sensitization and then to CBD. We used calculation...

BACKGROUND Beryllium exposure occurs in aluminium smelters from natural contamination of bauxite, the principal source of aluminium. AIMS To characterize beryllium exposure in aluminium smelters and determine the prevalence rate of beryllium sensitization (BeS) among aluminium smelter workers. METHODS A population of 3185 workers from nine aluminium smelters owned by four different aluminiu...

Respiratory sensitization can be caused by a variety of substances at workplaces, and the health and economic burden linked to allergic respiratory diseases continues to increase. Although the main factors that affect the onset of the symptoms are the types and intensity of allergen exposure, there is a wide range of interindividual variation in susceptibility to occupational/environmental sens...

BACKGROUND Up to 12% of beryllium-exposed American workers would test positive on beryllium lymphocyte proliferation test (BeLPT) screening, but the implications of sensitization remain uncertain. METHODS Seventy two current and former employees of a beryllium manufacturer, including 22 with pathologic changes of chronic beryllium disease (CBD), and 50 without, with a confirmed positive test ...

Following paper presents current studies on beryllium block poisoning based on beryllium moderated research reactor MARIA. Description of the problem was given along with calculation and measurement methodology. At the moment the experimental campaign is still under development.

I n the late 1990s, leaders in a company that manufactures beryllium materials began a process to re-examine the effectiveness of the existing beryllium safety model. This model was based on the primary goals of keeping worker exposure below 2 μg/m3 time-weighted average (TWA) as determined by the daily weightedaverage (DWA) method and prevention of beryllium migration to home and the community...

Granulomatous lung diseases are a heterogeneous group of disorders that have a wide spectrum of pathologies with variable clinical manifestations and outcomes. Precise clinical evaluation, laboratory testing, pulmonary function testing, radiological imaging including high-resolution computed tomography and often histopathological assessment contribute to make a confident diagnosis of granulomat...