The non-H atoms of the cation of the title salt, C(8)H(9)N(4)O(+)·Cl(-), are approximately co-planar (r.m.s. deviation = 0.024 Å) with one amino group forming an intra-molecular hydrogen bond to the tertiary N atom of the benzoxazole fused-ring system. The cations and anions are linked by cyclic R(2) (1)(6) N-H⋯Cl hydrogen-bonding associations, generating linear chains running along the a-axis ...

The title compound, C(20)H(16)NO(3)P, was synthesized by the addition of diphenyl-phosphine chloride to a tetra-hydro-furan solution of Et(3)N and 2-methyl-1,3-benzoxazol-4-ol at 233 K. In the mol-ecule, the almost planar (r.m.s. deviation = 0.010 Å) benzoxazole moiety is attached to the slightly distorted tetra-hedral P atom [C-P-C-C torsion angle = 132.20 (18)°]. The crystal structure does no...

The enol-keto tautomerism of 2-(2’-hydrophenyl)benzoxazole (HBO) in its metastable triplet states has been studied in fluid, non-polar solution. After laser flash excitation the keto triplet state is populated with high efficiency. The establishment of a ketoenol equilibrium was observed between 55 and 220 K. At low temperatures the rate of this reaction is determined by tunnel effects. The bar...

A novel triptycene-based ligand with a preorganized framework was designed to model carboxylate-bridged diiron active sites in bacterial multicomponent monooxygenase (BMM) hydroxylase enzymes. The synthesis of the bis(benzoxazole)-appended ligand L1 depicted was accomplished in 11 steps. Reaction of L1 with iron(II) triflate and a carboxylate source afforded the desired diiron(II) complex [Fe(2...

In vivo visualization of a-synuclein deposition by carbon-11-labelled 2-[2-(2-dimethylaminothiazol5-yl)ethenyl]-6-[2-(fluoro)ethoxy]benzoxazole positron emission tomography in multiple system atrophy Akio Kikuchi, Atsushi Takeda, Nobuyuki Okamura, Manabu Tashiro, Takafumi Hasegawa, Shozo Furumoto, Michiko Kobayashi, Naoto Sugeno, Toru Baba, Yasuo Miki, Fumiaki Mori, Koichi Wakabayashi, Yoshihit...

Streptomyces sp. strain NTK 937 is the producer of the benzoxazole antibiotic caboxamycin, which has been shown to exert inhibitory activity against Gram-positive bacteria, cytotoxic activity against several human tumor cell lines, and inhibition of the enzyme phosphodiesterase. In this genome announcement, we present a draft genome sequence of Streptomyces sp. NTK 937 in which we identified at...