Zinc sulphate and boric acid ophthalmic preparations, containing benzalkonium chloride as preservative, have been investigated against gram-negative and positive bacteria. Viability of bacteria was found after 7 days, although it was completely suppressed after 24 hours of inoculation. Zinc sulphate generally increases the antimicrobial activity of benzalkonium chloride, whereas boric acid ...

OBJECTIVE To measure the influence of topical steroids and the preservative potassium sorbate on the ciliary beat frequency (CBF) of human nasal mucosa in vitro. DESIGN In vitro study of cultured ciliated cells of human nasal mucosa. METHODS Human nasal mucosa was removed endoscopically and cultured for 10 days. Cell cultures with ciliated cells grown on an object slide were exposed to benz...

Apart from their release of fluorine ions, GICs can potentially be used as templates for the release of other active antimicrobial ingredients. The aim of this study was to investigate the possibility of incorporating an antimicrobial compound into a glass-ionomer cement. For the realization of the aim set we used the commercially available ChemFlex glass-ionomer cement, a material widely used ...

BACKGROUND Resistance toward quaternary ammonium compounds (QACs) is widespread among a diverse range of microorganisms and is facilitated by several mechanisms such as biofilm formation. OBJECTIVES In this study, the effects of benzalkonium chloride on planktonic growth and biofilm formation by some field isolates of animal bacterial pathogens were investigated. MATERIALS AND METHODS Forty...

AIM To report periorbital dermatitis as a late side effect of topical dorzolamide hydrochloride (Trusopt), a drug used to reduce intraocular pressure. METHODS A retrospective study of 14 patients who developed periorbital dermatitis while using topical dorzolamide hydrochloride was undertaken. Six patients underwent patch testing for sensitivity to Trusopt, dorzolamide hydrochloride, and the ...

Antimicrobial chemicals are widely applied to clean and disinfect food-contacting surfaces. However, the cellular response of bacteria to various disinfectants is unclear. In this study, the physiological and genome-wide transcriptional responses of Bacillus cereus ATCC 14579 exposed to four different disinfectants (benzalkonium chloride, sodium hypochlorite, hydrogen peroxide, and peracetic ac...

Antimicrobial chemicals are widely applied in the food processing industry. In attention to extent uses of disinfectants, it is necessary to evaluate and certificate the efficacy of disinfectants and employing the minimum effective dosages. In this research the antibacterial influences of a common disinfectant solution used in food industry, benzalkonium chloride that is a quaternary ammonium c...

To evaluate corneal sensitivity by using the Cochet-Bonnet® esthesiometer in normal canine eyes at different time points following instillation of three different topical non-steroidal anti-inflammatory drugs (flurbiprofen sodium 0.03%, diclofenac sodium 0.1% and ketorolac tromethamine 0.5%) and benzalkonium chloride 0.01%. Six healthy mixed breed dogs from the same litter were used in two diff...