Long-term trends of atmospheric Quercus pollen recorded for 25 years (1995–2019) in southern Spain (Cordoba city, Andalusia region) have been studied to determine the influence climate fluctuations and other anthropogenic factors on Mediterranean oak vegetation areas. Atmospheric analysis revealed different changes reproductive phenology through study period. Pollination intensity showed an ave...

MicroRNAs (miRNAs) are small, non-coding RNAs that function as key post-transcriptional regulators in neural development, brain function, and neurological diseases. Growing evidence indicates that miRNAs are also important mediators of nerve regeneration, however, the affected signaling mechanisms are not clearly understood. In the present study, we show that nerve injury-induced miR-431 stimul...

Synapse loss is well regarded as the underlying cause for the progressive decline of memory function over the course of Alzheimer’s disease (AD) development. Recent observations suggest that the accumulation of the Wnt antagonist Dickkopf-1 (Dkk1) in the AD brain plays a critical role in triggering synaptic degeneration. Mechanistically, Dkk1 cooperates with Kremen1 (Krm1), its transmembrane re...

A reinvestigation of a Fijian collection of Cacospongia mycofijiensis has yielded the known mycothiazole and a novel heterocyclic, CTP-431 (1). Its structure including absolute configuration as 8R,9R,10S,13S was established using NMR data, calculated DFT (13)C chemical shifts and results from X-ray crystallography. It is possible that the tricyclic skeleton of CTP-431 (1) is biosynthetically re...

The problem of ricochet of any projectile when it fails to hit the target or ifter its impact on the target, is of great importawe for the services as well as for the police personnel. The ricochet process is of constant concern for the Airforce authorities also during air to ground attack, due to the chances of hit to own a h a & from own fire. Whenever any bullet hits the pound short of targe...