The optimization of biomass loading enzyme loading, surfactant concentration and incubation time, using response surface methodology (RSM) and Box Behnken design for enzymatic saccharification of sugarcane tops (SCT) for maximum recovery of fermentable sugars using crude cellulases, resulted in 90.24% saccharification efficiency. Maximum saccharification yield of 0.376 g/g glucose as substrate ...

Current research has been done to develop statistically and optimized immediate release tablets for eslicarbazepine. Nineteen formulations of eslicarbazepine acetate are prepared by wet granulation. The three-dimensional Box-Behnken design at three levels (33) was developed study how selected independent variables affect dependent responses. After the initial test, items were as follows; polyvi...

Nanoliposomes are bilayer phospholipid vesicles used to encapsulate and deliver therapeutic agents. The study was aimed investigate the effects of critical variables on nanoliposomes characteristics. Imatinib mesylate-loaded were formulated by two-step emulsification process using a high-speed homogenizer system probe-type ultrasonicator. Box-Behnken design utilized optimize parameters. mean pa...

While chiral 2,3-Butanediol (2,3-BD) is currently receiving remarkable attention because of its numerous industrial applications in the synthetic rubber, bioplastics, cosmetics, and flavor industries, 2,3-BD-mediated feedback inhibition of Paenibacillus polymyxa DSM 365 limits the accumulation of higher concentrations of 2,3-BD in the bioreactor during fermentation. The Box-Behnken design, Plac...

This paper presents the micro-finishing of bevel gears by electrochemical-mechanical finishing (ECMF) process under different experimental conditions of current, rotating speed of workpiece and electrolyte concentration. These different experimental conditions are planned on the basis of box behnken design (BBD) design of experiments (DOE) technique of response surface methodology (RSM). An emp...

This paper discusses the use of Box Behnken design approach to plan the experiments for turning Inconel 718 alloy with an overall objective of optimizing the process to yield higher metal removal, better surface quality and lower cutting forces. Response Surface methodology (RSM) has been adopted to express the output parameters (responses) that are decided by the input process parameters. RSM ...