نتایج جستجو برای: behavioral profiling

تعداد نتایج: 231278  

Journal: :Neuron 2016
Ellen J. Hoffman Katherine J. Turner Joseph M. Fernandez Daniel Cifuentes Marcus Ghosh Sundas Ijaz Roshan A. Jain Fumi Kubo Brent R. Bill Herwig Baier Michael Granato Michael J.F. Barresi Stephen W. Wilson Jason Rihel Matthew W. State Antonio J. Giraldez

Autism spectrum disorders (ASDs) are a group of devastating neurodevelopmental syndromes that affect up to 1 in 68 children. Despite advances in the identification of ASD risk genes, the mechanisms underlying ASDs remain unknown. Homozygous loss-of-function mutations in Contactin Associated Protein-like 2 (CNTNAP2) are strongly linked to ASDs. Here we investigate the function of Cntnap2 and und...

Journal: :Immunity 2016
Thomas Blank Claudia N Detje Alena Spieß Nora Hagemeyer Stefanie M Brendecke Jakob Wolfart Ori Staszewski Tanja Zöller Ismini Papageorgiou Justus Schneider Ricardo Paricio-Montesinos Ulrich L M Eisel Denise Manahan-Vaughan Stephan Jansen Stefan Lienenklaus Bao Lu Yumiko Imai Marcus Müller Susan E Goelz Darren P Baker Markus Schwaninger Oliver Kann Mathias Heikenwalder Ulrich Kalinke Marco Prinz

Sickness behavior and cognitive dysfunction occur frequently by unknown mechanisms in virus-infected individuals with malignancies treated with type I interferons (IFNs) and in patients with autoimmune disorders. We found that during sickness behavior, single-stranded RNA viruses, double-stranded RNA ligands, and IFNs shared pathways involving engagement of melanoma differentiation-associated p...

Journal: :iranian biomedical journal 0
احمد رضا بهره مند ahmad r. bahrmand مهرداد بابایی mehrdad h. babaie نادر شاهرخی nader shahrokhi محمد مهدی فیض آبادی mohammad m. feizabadi valery v. bakayev

three tuberculous, twenty-one non-tuberculous mycobacterial (ntm) reference strains and seventy two isolates classified by biochemical tests were shown to produce specific sets of dna fragments in a polymerase chain reaction with single universal primer (up-pcr). a rather wide limit of tolerance for variations in procedure of pcr mixture preparation and thermocycling parameters was found. there...

Journal: :management studies and economic systems 2015
m. prasanna mohan raj mohammed sait a k

the current youth market is characterized as tech-savvy, variety seekers who has been active in using digital technology in unprecedented ways. the market segment defined here comprises of youth adults between the ages 20 to 30, who are more comfortable with purchasing the smartphones than previous generation. there is fierce competition in smartphone market, due to the large selection of devic...

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