Like most coronaviruses, the coronavirus mouse hepatitis virus (MHV) exhibits strong species specificity, causing natural infection only in mice. MHV-A59 virions use as a receptor a 110- to 120-kDa glycoprotein (MHVR) in the carcinoembryonic antigen (CEA) family of glycoproteins (G. S. Dveksler, M. N. Pensiero, C. B. Cardellichio, R. K. Williams, G. S. Jiang, K. V. Holmes, and C. W. Dieffenbach...

The experimental antitumor activity and toxicity of a new antibiotic, BBM 928A (Luzopeptin A), was evaluated in mice. When administered as a suspension in 0.9% NaCI solution, the compound demonstrated good activity [median survival time of dying mice in a drug-treated group divided by the median survival time of 0.9% NaCI solution-treated mice in a tumor control group, (T/C) >150%] against ¡.p...

This Letter presents a technique for subdiffraction limit imaging termed Bessel beam microscopy (BBM). By placing a lens in series with an axicon in the optical path of a microscope, the diffraction-limited resolution of the base microscope is improved by one third. This improvement is demonstrated experimentally by resolving individual subdiffraction limit fluorescent beads in a close-pack arr...

Fredkin’s Billiard Ball Model (BBM) is considered one of the fundamental models of collision-based computing, and it is essentially based on elastic collisions of mobile billiard balls. Moreover, fixed mirrors or reflectors are brought into the model to deflect balls to complete the computation. However, the use of fixed mirrors is “physically unrealistic” and makes the BBM not perfectly moment...

Single anatomical variation in the upper limb is common, but the coexistence of neuromuscular anomalies is still rare. We found a combined neuromuscular variation in the upper limb in a 61-year-old Korean male cadaver, whose cause of death was laryngeal carcinoma, during a routine dissection course for medical students. In his left arm, a supernumerary head of the biceps brachii muscle attached...

This paper discusses the existence and stability of solitary-wave solutions of a general higher-order Benjamin-Bona-Mahony (BBM) equation, which involves pseudo-differential operators for the linear part. One of such equations can be derived from water-wave problems as second-order approximate equations from fully nonlinear governing equations. Under some conditions on the symbols of pseudo-dif...

We investigate the well-posedness of a class of nonlinear dispersive waves on trees, in connection with the mathematical modeling of the human cardiovascular system. Specifically, we study the Benjamin-Bona-Mahony (BBM) equation, also known as the regularized long wave equation, posed on finite trees, together with standard junction and terminal boundary conditions. We prove that the Cauchy pro...

Ezetimibe inhibits Niemann-Pick C1-like 1 (NPC1L1), an apical membrane cholesterol transporter of enterocytes, thereby reduces intestinal cholesterol absorption. This treatment also increases extrahepatic reverse cholesterol transport via an undefined mechanism. To explore this, we employed a trans-intestinal cholesterol efflux (TICE) assay, which directly detects circulation-to-intestinal lume...

Streptozotocin-induced (Type 1) diabetes mellitus (T1DM) in rats promotes jejunal glucose transport, but the trigger for this response remains unclear. Our recent work using euglycemic rats has implicated the enterocyte renin-angiotensin system (RAS) in control of sodium-dependent glucose transporter (SGLT1)-mediated glucose uptake across the jejunal brush border membrane (BBM). The aim of the ...