Cytochrome P450 monooxygenases (CYPs/P450s) are heme-thiolate proteins whose role as a drug target against pathogenic microbes has been explored because of their stereo- and regio-specific oxidation activity. We aimed to assess the CYP53 family's role as a common alternative drug target against animal (including human) and plant pathogenic fungi and its role in fungal-mediated wood degradation....

In the course of our search for new bioactive compounds from basidiomycetes, four new compounds were isolated from fermentations of Limacella illinita. Illinitone A (1) exhibited weak phytotoxic and moderate nematicidal activities against Caenorhabditis elegans, illinitone B (2) was moderately cytotoxic, while limacellone (3) exhibited weak cytotoxic and phytotoxic activities. The muurolane ses...

We have developed a DNA-based assay to reliably detect brown rot and white rot fungi in wood at different stages of decay. DNA, isolated by a series of CTAB (cetyltrimethylammonium bromide) and organic extractions, was amplified by the PCR using published universal primers and basidiomycete-specific primers derived from ribosomal DNA sequences. We surveyed 14 species of wood-decaying basidiomyc...

The gradual elimination of chromium from wood preservative formulations results in higher Cu leaching and increased susceptibility to wood decay fungi. Finding a sustainable strategy in wood protection has become of great interest among researchers. The objective of these in vitro studies was to demonstrate the effect of T-720-enriched organic charcoal (biochar) against five wood decay basidiom...

The potential of wood-rotting and litter-deconstructing basidiomycetes to convert lignocellulose into a wide variety products has been extensively studied. In particular, basidiomycete secretomes are attracting much attention from researchers biotechnology companies due their ability produce extracellular hydrolytic oxidative enzymes that effectively degrade cellulose, hemicellulose, lignin pla...

antimicrobial activity of different culture extract of oudemansiella sp grown on liquid medium (mygp) were tested. different fungi (c. albicans, c. lipolytica, saccharomyces cervisiea, cladosporium herbarum, and aspergillus niger) and bacteria (microccocus luteus, e. coli, staphylococcus aureus, and staphylococcus epidermidis) were used as test organisms. various antimicrobial assay methods inc...

Abstract Background: Increase of nitrate concentration in water sources is becoming a serious problem in many parts of the world. Nitrogen containing compounds released into environment can create serious problems, such as eutrophication of water sources and hazard potential to human health, because it has potency of causing methemoglubinemia disease and cancer. Between recommended methods, bi...

in the present study, four carbon sources were tested for the polyester synthesis of pseudomonas aeruginosa pa01 which is a ubiquitous environmental bacterium and is one of the top three causes of opportunistic human infections. these included linear c8 to c11 carboxylic acids. octanoic acid, nonanoic acid, decanoic acid and undecanoic acid were added to m1 minimal medium to final concentration...

The production of new generation of wood preservatives (without addition of a co-biocide) in combination with an exchange of wood poles on identical sites with high fungal inoculum, has resulted in an increase of premature failures of wood utility poles in the last decades. Wood destroying basidiomycetes inhabiting sites where poles have been installed, have developed resistance against wood pr...