Background Cure rates for chronic hepatitis C have improved dramatically with direct-acting antivirals (DAAs), but treatment barriers remain. We aimed to compare treatment initiation rates and barriers across both interferon-based and DAA-based eras. Methods We conducted a retrospective cohort study of all patients with chronic hepatitis C seen at an academic hepatology clinic from 1999 to 20...

Porunar, Pulavar, Panar, Koudhar, Patini, Varaviyar are known as Iravalars (beggers). They called because they earn their living by singing. In songs, praise the rich people and gift, get gifts, money so on. The also go in search of Iravalars, love to hear songs them. Sangha literary texts speaks abundantly extensively about how income singing others.

karim khan can be considered as the only authoritative king in the whole zand era, thus the cultural and artistic foundations of this vary era is related to his government and him. seemingly, he was uneducated; however, he was interested in art, literature, and science. therefore, his court was the concourse of scientists, scholars, and artists. moreover, he has supported so many architectural ...

the present study is investigating the role and situation of women in parthian period. the role of women in parthian era based on archaeological evidences and historical literatures is unknown. the literature had a brief look to this and even leading to the misunderstanding. such literatures concerning generally to the women and their personal attributes in the court like political marriages. i...

Oncogenesis in breast cancer often requires the overexpression of the nuclear receptor coactivator AIB1/SRC-3 acting in conjunction with estrogen receptor-a (ERa). Phosphorylation of both ERa and AIB1 has been shown to have profound effects on their functions. In addition, proteasome-mediated degradation plays a major role by regulating their stability and activity. CK1d, a member of the ubiqui...