نتایج جستجو برای: barnes maze
تعداد نتایج: 13229 فیلتر نتایج به سال:
We discuss the determination of the infrared singularities of massive one-loop 5-point functions with Mellin-Barnes (MB) representations. Massless internal lines may lead to poles in the ε expansion of the Feynman diagram, while unresolved massless final state particles give endpoint singularities of the phase space integrals. MB integrals are an elegant tool for their common treatment. An eval...
PURPOSE Pilocarpine induces prolonged status epilepticus (SE) in rodents that results in neurodegeneration and cognitive deficits, both commonly observed to be associated with human temporal lobe epilepsy. The multifunctional neuronal modulator, cyclooxygenase-2 (PTGS2 or COX-2), is rapidly induced after SE, mainly in principal neurons of the hippocampal formation and cortex. We used mice in wh...
Obesity arising due to the dietary and life style changes is fast reaching epidemic proportions all over the world. There is increasing evidence that the incidence of Alzheimer disease (AD) is significantly influenced by a cluster of metabolic diseases, including diabetes and obesity. This study was aimed to test the suitability of experimentally-induced obesity in rats as an experimental anima...
Observational studies in humans have found associations between overstimulation in infancy via excessive television viewing and subsequent deficits in cognition and attention. We developed and tested a mouse model of overstimulation whereby p10 mice were subjected to audio (70 db) and visual stimulation (flashing lights) for six hours per day for a total of 42 days. 10 days later cognition and ...
Abstract Introduction A pressing issue in modern society, lack of sleep has detrimental health consequences, among which cognitive dysfunctions attract great attention. Although there is consensus about the harmful effects insufficient on vigilance and attention, still a debate memory susceptibility to acute chronic deprivation. Which types are more vulnerable remains unclear. We studied spatia...
Tauopathies are neurodegenerative disorders characterized by the accumulation of abnormal tau protein leading to cognitive and/or motor dysfunction. To understand the relationship between tau pathology and behavioral impairments, we comprehensively assessed behavioral abnormalities in a mouse tauopathy model expressing the human P301S mutant tau protein in the early stage of disease to detect i...
CB 1 receptor-compromised animals show profound deficits in extinguishing learned behavior from aversive conditioning tasks, but display normal extinction learning in appetitive operant tasks. However, it is difficult to discern whether the differential involvement of the endogenous cannabinoid system on extinction results from the hedonics or the required responses associated with the disparat...
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