نتایج جستجو برای: bacterial surface display

تعداد نتایج: 971613  

2016
Sofie Wendel Emil C. Fischer Virginia Martínez Susanna Seppälä Morten H. H. Nørholm

BACKGROUND Bacterial surface display is an attractive technique for the production of cell-anchored, functional proteins and engineering of whole-cell catalysts. Although various outer membrane proteins have been used for surface display, an easy and versatile high-throughput-compatible assay for evaluating and developing surface display systems is missing. RESULTS Using a single domain antib...

Journal: :Applied and environmental microbiology 2000
Y S Kim H C Jung J G Pan

The bacterial surface display method was used to selectively screen for improved variants of carboxymethyl cellulase (CMCase). A library of mutated CMCase genes generated by DNA shuffling was fused to the ice nucleation protein (Inp) gene so that the resulting fusion proteins would be displayed on the bacterial cell surface. Some cells displaying mutant proteins grew more rapidly on carboxymeth...

Journal: :FEMS microbiology letters 2003
Su-Min Kang Jin-Kyu Rhee Eui-Joong Kim Kwang-Hyub Han Jong-Won Oh

Cell surface expression of protein has been widely used to display enzymes and antigens. Here we show that Pseudomonas syringae ice nucleation protein with a deletion of internal repeating domain (INC) can be used in Escherichia coli to display peptide in a conformationally active form on the outside of the folded protein by fusing to the C-terminus of INC. Diagnostic potential of this technolo...

Journal: :Journal of bacteriology 2001
R Isticato G Cangiano H T Tran A Ciabattini D Medaglini M R Oggioni M De Felice G Pozzi E Ricca

We developed a novel surface display system based on the use of bacterial spores. A protein of the Bacillus subtilis spore coat, CotB, was found to be located on the spore surface and used as fusion partner to express the 459-amino-acid C-terminal fragment of the tetanus toxin (TTFC). Western, dot blot and fluorescent-activated cell sorting analyses were used to monitor TTFC surface expression ...

Journal: :European Journal of Biochemistry 2000

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