Bacopa monnieri extract has been implicated in the recovery of memory impairments due to various neurological disorders in animal models and humans. However, the precise molecular mechanism of the role of CDRI-08, a well characterized fraction of Bacopa monnieri extract, in recovery of the diabetes mellitus-induced memory impairments is not known. Here, we demonstrate that DM2 mice treated oral...

The present study was undertaken to compare medicinal plants against mixed anxiety-depressive disorder (MAD) to evaluate their potency in combating MAD disorders. Previous studies from our lab have shown that Bacopa monniera (BM), and Panax quniquefolium (PQ) have significant adaptogenic properties. Hence, we have further confirmed their activity in stress related disorders like anxiety and dep...

INTRODUCTION The Bacopa monnieri is traditional Ayurvedic medicine, and reported for memory-enhancing effects. The Bacoside is poorly soluble, bitter in taste and responsible for the memory enhancement action. Memory enhancer is commonly prescribed for children or elder people. OBJECTIVE Poor solubility, patient compliance and bitterness were a major driving force to develop taste masked β-cy...

Background: The Ayurvedic medicinal system employs a holistic approach to health, utilising the synergistic properties of organic resources. Research into the Ayurvedic herb Bacopa monnieri (L.) Wettst. (B.monnieri) has reported improvements in cognitive outcomes in child and adult populations. The aim of current review is to systematically assess and critically summarize clinical trials invest...

An efficient micropropagation protocol of Bacopa monnieri (L.) Pennell through two-stage culture nodal segments and ex vitro acclimatizationShashikanta Behera, Nibedita Nayak, Shasmita, Durga P. Barik, Soumendra K. Naik

1. The Indian Herbal Pharmacoepia. Regional Research Laboratory and Indian Drug Manufacturers Association. Mumbai: IDMA; 2002. p. 467. 2. Archana R, Namasivayam A. Antistressor effect of Withania somnifera. J Ethnopharmacol 1999;64:91-3. 3. Jha NK, Jha AK. Bacopa monnieri: Brahmi. Phytopharm 2005;11:3-14. 4. Gupta AP, Mathur S. High performance thin layer chromatography method for determination...

Several studies have indicated a chronic cognitive enhancing effect of Bacopa monnieri across different ages and cognitive impairment associated with vitamin and mineral deficiencies in children. Therefore, we investigated the effects of 4-month supplementation with a combination of B. monnieri extract and multiple micronutrients on cognitive functions in Indian school children aged 7-12 years....

Contents 1. Introduction 1.1 Neurodegenerative disease in perspective 1.2. Searching for symptoms in traditional medicine 1.3. Approaches to scientific investigation 1.4. Plants as a source of useful therapeutic agents in neurodegenerative diseases 2. Plants and their constituents from Ayurvedic medicine 2.1 Withania somnifera 2.2. Bacopa monniera 2.3. Centella asiatica 2.4. Mucuna pruriens 3. ...

Diabetic neuropathic pain is generally considered to be one of the most troublesome complications affecting diabetic patients and current therapy provides inadequate pain relief. In the present study, the neuroprotective effect of Bacopa monnieri, Linn. (Brahmi, BM) targeted at adenosine receptor was studied in a model of diabetic neuropathic pain. Diabetes was induced by streptozotocin (65 mg/...