نتایج جستجو برای: azoles

تعداد نتایج: 1992  

Amir Arastefar, Parisa Badiee

Invasive fungal infections with high mortality rate are a growing health concern in hospitals and medical centers. The infection usually occurs in people with compromised immune systems. The purpose of this paper is a review of the most commonly prescribed antifungal drugs for invasive fungal diseases. Antifungals consist of the four main groups; polyenes, azoles, echinocandins and DNA an...

Leishmaniasis is a group of tropical diseases with high worldwide prevalence and difficulty in management. At present, the development of resistance and the increase of co-infected leishmaniasis with AIDS have become a serious public health problem. Thus, designing and discovery of effective and non-toxic drugs for the treatment of this disease is very urgent. Azole derivatives have displayed a...

Journal: :Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009
D M Te Loo R M van Schie P M Hoogerbrugge

10049 Background: Vincristine is one of the corner stitches in the treatment of children with acute lymphoblastic leukemia (ALL). Constipation and other peripheral and central neurotoxicities are the most common side effects. Drugs interfering with the metabolism of vincristine might potentiate these side effects. A group of drugs that interact with the metabolism of vincristine are azoles. Sev...

Journal: :Antimicrobial agents and chemotherapy 2015
R H Jensen H K Johansen L M Søes L E Lemming F S Rosenvinge L Nielsen B Olesen L Kristensen E Dzajic K M T Astvad M C Arendrup

The prevalence of intrinsic and acquired resistance among colonizing Candida isolates from patients after candidemia was investigated systematically in a 1-year nationwide study. Patients were treated at the discretion of the treating physician. Oral swabs were obtained after treatment. Species distributions and MIC data were investigated for blood and posttreatment oral isolates from patients ...

Journal: :Antimicrobial Agents and Chemotherapy 1998

Journal: :Bioenergetics: Open Access 2016

2010
Chiung-Kuang Chen Siegfried S. F. Leung Christophe Guilbert Matthew P. Jacobson James H. McKerrow Larissa M. Podust

BACKGROUND Chagas Disease is the leading cause of heart failure in Latin America. Current drug therapy is limited by issues of both efficacy and severe side effects. Trypansoma cruzi, the protozoan agent of Chagas Disease, is closely related to two other major global pathogens, Leishmania spp., responsible for leishmaniasis, and Trypansoma brucei, the causative agent of African Sleeping Sicknes...

2007
Michael A Pfaller Daniel J Diekema Michael E Klepser Thomas R Rogers Elizabeth M Johnson Peter Donnelly Zeina A Kanafani Jörg Janne Vehreschild

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