In this short paper we solve in general the problem of synchronization of lights in a street or avenue of having two directions assuming that the all vehicles have a constant speed. The general approach is elementary and the case for practical application is vast. Some relations with other works are presented.

Inhibition of Ras-stimulating enzymes is a possible avenue to treat Ras-driven diseases. In this issue of Chemistry & Biology, Evelyn and coworkers report an inhibitor for one such enzyme, Sos1, capable of impairing wild-type Ras signaling in cells.