نتایج جستجو برای: auto reactive cell
تعداد نتایج: 1821202 فیلتر نتایج به سال:
Hematopoietic stem cell transplantation (HSCT) is considered a potentially curative therapy for a number of severe autoimmune diseases. The rationale consists of deleting auto-reactive T and/or B cell clones and re-constructing a functional immune system tolerant to autoantigens. The re-emergence of T cell immunity following myeloablation largely depends on thymic de novo production of naïve T ...
Recent successes in tumor immunotherapies have highlighted the importance of tumor immunity. However, most of the work conducted to date has been on T cell immunity, while the role of B cell immunity in cancer remains more elusive. In this study, immunogenetic repertoire profiling for tumor-infiltrating B and T cells in gastric cancers was carried out to help reveal the architecture of B cell i...
OBJECTIVE Antibody subclasses reflect specific immunological processes and may be indicative of the underlying pathological pattern in an autoimmune disease like RA. We therefore quantified anti-cyclic citrullinated peptides (CCP) and anti- citrullinated vimentin (MCV) IgG subclass titres in RA patients and compared them with the respective titres of antibodies directed against the varicella zo...
Objective. Antibody subclasses reflect specific immunological processes and may be indicative of the underlying pathological pattern in an autoimmune disease like RA. We therefore quantified anti-cyclic citrullinated peptides (CCP) and anticitrullinated vimentin (MCV) IgG subclass titres in RA patients and compared them with the respective titres of antibodies directed against the varicella zos...
multiple sclerosis (ms) is an autoimmune disease in which auto-reactive t cells react with self-antigens expressed in the central nervous system (cns). the main cause of ms is unknown. nonetheless, the most probable theory is based on molecular mimicry, which suggests that some infections can activate t cells against brain auto-antigens like myelin proteolipid protein (plp) and initiate the dis...
در این تحقیق استفاده از کربن اکتیو ، نانوذرات مغناطیسی آهن و نانو کامپوزیت آهن در بستر کربن اکتیو، برای حذف رنگهای reactive ) آنیونی( از پسابها مورد مطالعه قرار گرفتند . رنگ reactive blue19,reactive red31 به عنوان مدلی از رنگهای آنیونی مورد بررسی قرار گرفت. مشخصات سطحی نانو ذرات آهن و نانو کامپوزیت آهن توسط sem ،tem،xrd مورد بررسی قرار گرفت . تاثیر عوامل مختلف (ph، مقدار جاذب، زمان تماس، دور هم...
BACKGROUND Islet cell transplantation can cure type 1 diabetes (T1D), but only a minority of recipients remains insulin-independent in the following years. We tested the hypothesis that allograft rejection and recurrent autoimmunity contribute to this progressive loss of islet allograft function. METHODOLOGY/PRINCIPAL FINDINGS Twenty-one T1D patients received cultured islet cell grafts prepar...
The authors describe a case of histiocyte-rich B-cell lymphoma (HR-BCL), a variant of diffuse large B-cell lymphoma, in a 51-year-old man. The patient presented with large axillary lymphadenopathy. Histopathologic and immunohistochemical examination of lymph node biopsy revealed diffuse effacement of the lymph node architecture by reactive histiocytes and neoplastic CD20 positive B cells. ...
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