In the State of Hawaii, there are abundant claims of benefit from cancer patients' use of the fruit juice of Morinda citrifolia (Noni). There is no well documented clinical report in peer review journals. The author here studiously examined 2 such claims through interview, review of the medical records and pathology slides. The author concludes that these cases are valuable experiences and hope...

The author describes aspects of social contezct that are of importance in the genesis of murdmous aiolnnce in childrm and adolescents. Case presentations illustrate the effects of family attachmcnt pathology, diffning outcomes in destru,ctiae child,rm, and, the copycat phmommon. The author concludes by summarizing the continuum of responses of childrm and ad,obscmts to aarious forms of threat: ...

The purpose of this study was to investipte the effects of metoclopramide on some gastrointestinal disorders. The author reports the results of a longitudinal study (since 1979 for 10 yrs) on 3700 patients with gastroesophageal reflux, heartburn, gastric peptic ulcer, gastritis, duodenitis, duodenal peptic ulcer and constipation due to decreas.ing intestinal peristaltism. The patients were 14-7...

This chapter introduces a framework for the design of serious games for learning, called the design, play, and experience framework. The author argues that the great potential of serious games will not be realized without a formal design approach. To that end, the author presents and thoroughly explains the design, play, and experience framework which provides a formal approach to designing the...

This article addresses the barriers to personalized medicine, focusing on the burgeoning field of biomarkers research. The author begins by framing intellectual property issues as more than a product of industry incentives and suggests that these issues are deeply entangled with other barriers facing personalized medicine such as regulatory framework deficiencies. The author proposes a set of f...

the exact cause or causes of hodgkin's disease have not yet been determined. the etiology of the disease suggests, but has not verified, a possible immunological and/or viral relationship. the article reviews the literature on the epidemiology and etiology of hodgkin’s disease from 1955 to the present. the author presents several clinical phenomena that are commonly associated with hodgkin’s di...

The author presents a review of the history of occupational health in Brazil, concerning the last 3 centuries. This period was divided into (a) slave labour, (b) immigrant labour, and (c) industrial labour. The author shows the early occupational diseases, pioneering occupational physicians and Brazilian laws on the subject. The creation of Fundacentro (Brazilian Foundation of Occupational Heal...

With insight grounded in his work for a national data collection consortium and as Vice President of Quality and Outcomes at the Children's Hospital of Wisconsin, the author connects the theory of pay-for-performance to the realities of its implementation. The author expands the Diagnosing the Data conversation by describing the challenges of collecting meaningful data and by addressing the pot...

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