In recent decades, studies referring to the activities of secondary compounds from plants have intensified, presenting great importance for pharmaceutical, biotechnological and agricultural industries. Therefore, objective this work was identify metabolites present in hydroethanolic leaf extract Libidibia ferrea (Mart. ex Tul.) L.P. Queiroz. To prepare extract, collected leaves were crushed con...

Until recently, pharmaceuticals used for the treatment of diseases have been based largely on the production of relatively small organic molecules synthesized by microbes or by organic chemistry. These include most antibiotics, analgesics, hormones, and other pharmaceuticals. Increasingly, attention has focused on larger and more complex protein molecules as therapeutic agents. This publication...

Tyrosinases and catechol oxidases belong to the family of polyphenol oxidases (PPOs). Tyrosinases catalyze theo-hydroxylation and oxidation of phenolic compounds, whereas catechol oxidases were so far defined to lack the hydroxylation activity and catalyze solely the oxidation of o-diphenolic compounds. Aurone synthase from Coreopsis grandiflora (AUS1) is a specialized plant PPO involved in the...

Introduction: Azadirachta indica A. Juss, popularly known as neem, has been gaining ground in alternative herbal medicine. This plant offers a constant source of new and unique phytochemicals that are used the development drugs. Aim: A preliminary chemical analysis was carried out to detect secondary metabolites present crude hydroethanolic extract dried macerated leaves evaluate its antioxidan...

Aurone synthase (AUS), a member of a novel group of plant polyphenol oxidases (PPOs), catalyzes the oxidative conversion of chalcones to aurones. Two active cgAUS1 (41.6 kDa) forms that differed in the level of phosphorylation or sulfation as well as the latent precursor form (58.9 kDa) were purified from the petals of Coreopsis grandiflora. The differing active cgAUS1 forms and the latent cgAU...