نتایج جستجو برای: atypical scid

تعداد نتایج: 54097  

Journal: :Infection and immunity 2001
H Q Jiang N A Bos J J Cebra

As a member of the indigenous gut mucosal microbiota, segmented filamentous bacteria (SFB) colonize the guts of a variety of vertebrates and invertebrates. They are potent microbial stimuli of the gut mucosal immune system. In the small intestines of mice and rats, it has been observed that SFB are absent during the suckling period and appear in high numbers shortly after weaning, then quickly ...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2009
Beatriz M Carreno Joel R Garbow Grant R Kolar Erin N Jackson John A Engelbach Michelle Becker-Hapak Leonidas N Carayannopoulos David Piwnica-Worms Gerald P Linette

PURPOSE Immunodeficient mice serve as critical hosts for transplantation of xenogeneic cells for in vivo analysis of various biological processes. Because investigators typically select one or two immunodeficient mouse strains as recipients, no comprehensive study has been published documenting differences in human tumor engraftment. Taking advantage of the increased metastatic potential of Rho...

Journal: :iranian journal of psychiatry 0
mitra hakim shooshtari department of psychiatry, mental health research center, iran university of medical sciences, tehran, iran rozita davari-ashtiani department of psychiatry, imam hossein hospital, shahid beheshti university of medical sciences, tehran, iran behavioral sciences research center, shahid beheshti university of medical sciences, tehran, iran zahra shahrivar department of psychiatry, roozbeh hospital, tehran university of medical sciences, tehran, iran psychiatry and psychology research center, tehran university of medical sciences, tehran, iran amir shabani department of psychiatry, mental health research center, iran university of medical sciences, tehran, iran yousef semnani department of psychiatry, imam hossein hospital, shahid beheshti university of medical sciences, tehran, iran hossein kaviani department of psychiatry, roozbeh hospital, tehran university of medical sciences, tehran, iran psychiatry and psychology research center, tehran university of medical sciences, tehran, iran

objective: to translate the structured clinical interview for dsm-iv axisi disorders (scid-i) into persian (farsi) and to adapt this instrument for the iranian culture. method: the scid was translated into persian using an elaborate procedure to achieve a satisfactory cross-cultural equivalent. this included forward translation by bilingual (english/persian) translators, discussion and revision...

Journal: :IEEE Access 2021

This paper proposes a downlink synchronization and cell identity (CID) estimation technique for cellular systems based on orthogonal time-frequency space (OTFS). In the proposed technique, each base station (BS) transmits one detection preamble (DP) two OTFS symbols (pilot secondary-CID (SCID) signal (SS)). The DP linear frequency-modulated (LFM) waveform, called proposed-LFM (pLFM), carries pr...

Journal: :The Journal of Experimental Medicine 1995
T A Bock D Orlic C E Dunbar H E Broxmeyer D M Bodine

We have generated immunodeficient scid-/scid- (SCID)-transgenic mice expressing the genes for human interleukin 3, granulocyte/macrophage-colony stimulating factor, and stem cell factor. We have compared engraftment and differentiation of human hematopoietic cells in transgenic SCID mice with two strains of nontransgenic SCID mice. Human bone marrow cells carrying the CD34 antigen or human umbi...

2015
Maïté Fransolet Laurie Henry Soraya Labied Marie-Caroline Masereel Silvia Blacher Agnès Noël Jean-Michel Foidart Michelle Nisolle Carine Munaut

BACKGROUND For women facing gonadotoxic treatment, cryopreservation of ovarian tissue with subsequent retransplantation during remission is a promising technique for fertility preservation. However, follicle loss within grafted ovarian tissue can be caused by ischemia and progressive revascularization. Several xenograft models using different immunodeficient rodent lines are suitable for studyi...

Journal: :Blood 1991
E K Waller O W Kamel M L Cleary A S Majumdar M R Schick M Lieberman I L Weissman

We reasoned that the SCID-hu mouse could provide an appropriate lymphoid or stromal microenvironment to support the growth of primary human lymphoma. Heterotransplantation of nine cases of primary T-cell non-Hodgkin's lymphoma (NHL) into untreated SCID mice and SCID mice reconstituted with human fetal thymus, spleen, and liver (SCID-hu) resulted in the development of lymphoid tumors in five (56...

2000
Norman R. Ruetsch Gayle C. Bosma Melvin J. Bosma

In severe combined immunodeficient (scid) mice, V(D)J recombination is severely impaired due to a recessive mutation ( scid ). Thus, we were surprised to find in this study that V l 1–J l 1 rearrangement is routinely detectable in scid fetal liver, adult bone marrow, and spleen in the apparent absence of completed VH–DJH and V k –J k rearrangements. Particularly surprising, we found the level o...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1990
M Reichman-Fried R R Hardy M J Bosma

Mice homozygous for the mutation scid (scid mice) are severely immunodeficient and generally lack detectable numbers of pre-B, B, and T cells. This condition is believed to result from a defect in the mechanism responsible for rearrangement of immunoglobulin and T-cell receptor genes in developing B and T lymphocytes. To test this hypothesis and evaluate whether scid affects only the process of...

2015
Chise Tateno Yosuke Kawase Yoshimi Tobita Satoko Hamamura Hiroki Ohshita Hiroshi Yokomichi Harumi Sanada Masakazu Kakuni Akira Shiota Yuha Kojima Yuji Ishida Hiroshi Shitara Naoko A. Wada Hiromi Tateishi Masayuki Sudoh Shin-ichiro Nagatsuka Kou-ichi Jishage Michinori Kohara Rafael Aldabe

We have used homozygous albumin enhancer/promoter-driven urokinase-type plasminogen activator/severe combined immunodeficient (uPA/SCID) mice as hosts for chimeric mice with humanized livers. However, uPA/SCID mice show four disadvantages: the human hepatocytes (h-heps) replacement index in mouse liver is decreased due to deletion of uPA transgene by homologous recombination, kidney disorders a...

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