نتایج جستجو برای: astrocytic tumors
تعداد نتایج: 181613 فیلتر نتایج به سال:
OBJECT Two to five percent of pediatric brain tumors are located in the thalamus. The optimal management for these tumors remains unclear. The aim of this study was to determine whether clinical and neuroimaging features could guide treatment, and to what extent these features, together with histological diagnosis and treatment modalities, influenced survival. METHODS The records of 69 childr...
Classifying adult gliomas remains largely a histologic diagnosis based on morphology; however astrocytic, oligodendroglial and mixed lineage tumors can display overlapping histologic features. We used multiplexed exome sequencing (OncoPanel) on 108 primary or recurrent adult gliomas, comprising 65 oligodendrogliomas, 28 astrocytomas and 15 mixed oligoastrocytomas to identify lesions that could ...
Astrocytomas are the most common pediatric brain tumors, accounting for 7%–8% of all childhood cancers. Relatively few studies have been performed on their molecular properties; therefore, classification of pediatric astrocytic tumors into genetic subtypes similar to that of adult tumors remains to be defined. Here, we report an extensive characterization of 44 pediatric astrocytomas—16 diffuse...
A clinicopathological study was made on 45 autopsy cases of brain tumors treated with radiotherapy. Morphological changes after radiotherapy were classified into six categories : 1) tumor disappearance, 2) small residual tumor, 3) extensive tumor necrosis, 4) proliferative tumor growth, 5) mixed glioblastoma and fibrosarcoma, and 6) no remarkable change. When the tumors are primarily radiosensi...
Introduction Retinal astrocytic hamartomas are benign tumors of the retinal nerve fiber layer with a characteristic appearance on ophthalmoscopic examination. Although these lesions may be found in isolation without systemic involvement, they usually occur in association with tuberous sclerosis. To our knowledge, there are few reports presenting optical coherence tomography(OCT)findings of vitr...
Background& Objective: Micro-vascular proliferation is an important histological feature of brain glioma with more vascular proliferation is present in higher grades of glioma. CD 105 is expressed in new actively proliferating and immature endothelial cells in tumor environment and appears to be capable to distinguish between malignant neo-vasculature and normal vesse...
Rearrangements concerning chromosome 9p are a late event in the progression of human astrocytic tumors to their most malignant form. The expression of PAX5, which maps to chromosome 9p13, was studied in primary human brain tumors of astrocytic origin. Whereas murine Pax5 is not expressed in the forebrain at any stage, PAX5 expression was increased in a range of astrocytomas (WHO grades II-IV) w...
BACKGROUND: Tumours form an integral part of disease process affecting the CNS and constitute a major part of all intracranial space occupying lesions. AIM: To study the histological findings of CNS tumors and to classify them according to WHO classification. MATERIALS AND METHODS: This is a five year study in which all the specimens of tumors of brain and spinal cord received in the department...
Most primary CNS tumors are astrocytic tumors. Glial classified according to histological criteria. The WHO classification for malignant gliomas in adults includes grades II through IV. Terms that classify grade astrocytomas (A), oligodendrogliomas (ODG), or mixed (GM). Grade III named similarly, and preceded by the word anaplastic, example, anaplastic astrocytoma (AA), oligodendroglioma (ODGA)...
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