نتایج جستجو برای: associated lipocalin

تعداد نتایج: 1521908  

Journal: :Stroke 2014
Changhong Xing Xiaoshu Wang Chongjie Cheng Joan Montaner Emiri Mandeville Wendy Leung Klaus van Leyen Josephine Lok Xiaoying Wang Eng H Lo

BACKGROUND AND PURPOSE We explored the hypothesis that injured neurons release lipocalin-2 as a help me signal. METHODS In vivo lipocalin-2 responses were assessed in rat focal cerebral ischemia and human stroke brain samples using a combination of ELISA and immunostaining. In vitro, microglia and astrocytes were exposed to lipocalin-2, and various markers and assays of glial activation were ...

2015
Hyung Eun Yim

Neutrophil gelatinase-associated lipocalin (NGAL) has emerged as one of the most promising biomarkers of renal epithelial injury. Numerous studies have presented the diagnostic and prognostic utility of urinary and plasma NGAL in patients with acute kidney injury, chronic kidney disease, renal injury after kidney transplantation, and other renal diseases. NGAL is a member of the lipocalin famil...

Journal: :Journal of the American Society of Nephrology : JASN 2007
Kai M Schmidt-Ott Kiyoshi Mori Jau Yi Li Avtandil Kalandadze David J Cohen Prasad Devarajan Jonathan Barasch

Neutrophil gelatinase-associated lipocalin (NGAL) is expressed and secreted by immune cells, hepatocytes, and renal tubular cells in various pathologic states. NGAL exerts bacteriostatic effects, which are explained by its ability to capture and deplete siderophores, small iron-binding molecules that are synthesized by certain bacteria as a means of iron acquisition. Consistently, NGAL deficien...

Journal: :iranian journal of medical sciences 0
amaneh mohammadi roushandeh raheleh halabian parisa mozafari jafar soleimani rad behnaz sadeghzadeh oskouei ali samadi kuchaksaraei

background: the effects of electromagnetic field (emf) on reproductive system have been of critical concern for a long time. it has been shown that the emf can adversely affect testicular cells and tissue and decrease male fertility. the most important determinants of male fertility are sperm development and motility, which are affected by changes in several factors including lipocalin 2 protei...

2017
Marcelo R. Bacci Ethel Z. Chehter Ligia A. Azzalis Beatriz Costa de Aguiar Alves Fernando L.A. Fonseca

Introduction Diabetic nephropathy is associated with specific histological changes. Early detection of poor glomerular and tubular function can be achieved with biomarkers of diabetes. The aim of this study was to evaluate the accuracy of kidney dysfunction biomarkers in type 2 diabetes (T2D). Methods Patients with T2D were grouped according to their glycated hemoglobin level. Patients' urine...

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