Sir—We read with interest the article by Pépin et al. [1], which reports that use of quinolones is a major risk factor for illness during an outbreak of Clostridium difficile–associated diarrhea (CDAD). These results confirm previous observations that quinolones and other antibiotics, such as third-generation cephalosporins, macrolides, broad-spectrumb-lactams, and aminoglycosides, are importan...
