background: in patients with acute stroke and middle cerebral artery (mca) stenosis, microembolic signals (mes) can predict further cerebral ischemia. therefore, this study was designed to evaluate the prevalence of mes by transcranial doppler (tcd) in patients with mca stenosis under treatment of aspirin or clopidogrel. methods: a randomized clinical trial was performed on 40 patients with acu...

This study investigated the role and mechanism of aspirin combined with rehabilitation training in nerve injury repair Schwann cell changes rats sciatic injury. Totally, 120 male healthy SD were randomly divided into sham, model, aspirin, + groups, 30 each group. The function index (SFI), photothermal pain tolerance threshold inclined plane test results at 4, 6, 8 weeks after operation compared...

Fatigue is recognized as one of the most disabling and frequent symptoms of multiple sclerosis (MS). Amantadine appears to have some proven ability to alleviate the fatigue in MS. The aim of this study was to assess the efficacy of co-administration of amantadine and aspirin for the treatment of fatigue in multiple sclerosis. Forty-five ambulatory patients aged 20–50 years with a diagnosis of M...

Renal artery stenosis (RAS) is the most common cause of secondary hypertension. Preliminary data indicate that aspirin renography with hippurate may be more sensitive for detection RAS. In this study 20 patients with known or suspected RAS underwent aspirin renography (20 mg/kg orally 1 hour before injection of radiotracer) and captopril renography (50 mg orally) with 99mTc-DTPA. Renal an...

purpose: to compare the effect of tissue plasminogen activator (tpa) and aspirin in patients with central retinal vein occlusion. methods: a prospective interventional study was conducted on patients with central retinal vein occlusion of less than 28 days' duration. patients in the tpa group received 100 μg intravitreal tissue plasminogen activator and the patients who declined intravitre...

background:   objective: to determine and compare uteroplacental circulation and obstetrics complications in pregnant women with pcos treated with metformin, aspirin and control group.   materials and methods: 105 pregnant women with pcos were enrolled in this study after assessing uterine artery pulsatility index (pi) with doppler ultrasonography at 12 weeks of gestation. the patients were div...

backgrounds and aims: methylglyoxal (mgo) is an –α, β dicarbonyl aldehyde inevitably produced from triose-phosphate intermediates of glycolysis, and amino acid. increased mgo in blood leads to alterations in coagulation, clot permeability and thus, atherosclerosis in children with diabetes; however, the precise mechanism is not clear. the present study aimed to compare different concentrations ...

the present study was carried out to determine whether helicobacter spp. infection in dogs could affect lesions caused by the non-steroidal anti-inflammatory drugs (nsaids), aspirin and celecoxib. thirty asymptomatic mixed-breed dogs were used for this study. gastric biopsies were taken via gastroscopy and evaluated by polymerase chain reaction (pcr) and rapid urease tests (rut). helicobacter s...

Background: Preeclampsia is one of the most common causes of maternal mortality. This complication has been attempted to prevent preeclampsia. Many drug treatments have also been tested, including aspirin, one of the drugs prescribed to prevent preeclampsia. Therefore, the present study was designed to summarize the findings and co...