Using the Swedish Medical Birth Registry (MBR), obstetrical and demographic information was retrieved for 250 children with autism or Asperger syndrome who were born in Malmoe, Sweden, and enrolled at the local Childand Youth Habilitation Center. The reference group consisted of all children born in Malmoe during 1980 – 2005. Obstetric sub-optimality (prematurity, low Apgar scores, growth restr...

Asperger syndrome (AS) is a subtype of Autism Spectrum Disorder (ASD) characterized by major problems in social and nonverbal communication, together with limited and repetitive forms of behavior and interests. The linguistic and cognitive development in AS is preserved which help us to differentiate it from other subtypes of ASD. However, significant effects of AS on cognitive abilities and br...

It has been proposed that the biological basis of autism spectrum disorder includes cerebellar 'disconnection'. However, direct in vivo evidence in support of this is lacking. Here, the microstructural integrity of cerebellar white matter in adults with Asperger syndrome was studied using diffusion tensor magnetic resonance tractography. Fifteen adults with Asperger syndrome and 16 age-IQ-gende...

Asperger Syndrome (AS) is a severe developmental disorder characterized by major difficulties in social interactio and restricted and unusual patterns of interest and behavior. There are many similarities with autism without retardation (or "Higher Functioning Autism"), and the issue of whether Asperger syndrome and Higher Functio Autism are different conditions is not resolved. To some extent,...

In human history, a great number of significant discoveries in medical science began with case studies. These include John Martin Harlow’s description of Phineas Gage in his letter to the editor of the Boston Medical and Surgical Journal, Alois Alzheimer’s report on his patient Auguste Deter, and the initial six children reported by Landau and Kleffner in 1957. Similarly, modern research on aut...

Asperger syndrome, first described by the Austrian physician Hans Asperger (1944), is an uncommon disorder whose clinical features overlap with those of autism (Kanner, 1943) and schizoid personality disorder (Wolff & Barlow, 1979; Wolff & Chick, 1980). Some authorities regard it as part of the "autistic spectrum" (Wing, 1981), while others have argued for the need to separate it from autism (R...

BACKGROUND During observation of the Necker cube perception becomes unstable and alternates repeatedly between a from-above-perspective ("fap") and a from-below-perspective ("fbp") interpretation. Both interpretations are physically equally plausible, however, observers usually show an a priori top-down bias in favor of the fap interpretation. Patients with Autism spectrum disorder are known to...

As investigações e evidências científicas apontam para necessidade de expandir o conhecimento acerca da síndrome Asperger. Esta pesquisa objetivou esclarecer como é a criança portadora Asperger bem como, quais são as suas necessidades peculiaridades. A metodologia utilizada bibliográfica, autores que discutem contribuem com seus resultados sobre tema abordado extrema relevância os educadores, p...

Previous studies have found a subgroup of people with autism or Asperger Syndrome who pass second-order tests of theory of mind. However, such tests have a ceiling in developmental terms corresponding to a mental age of about 6 years. It is therefore impossible to say if such individuals are intact or impaired in their theory of mind skills. We report the performance of very high functioning ad...