نتایج جستجو برای: asian continental ancestry group

تعداد نتایج: 1066264  

Journal: :Genetics 2015
Yambazi Banda Mark N Kvale Thomas J Hoffmann Stephanie E Hesselson Dilrini Ranatunga Hua Tang Chiara Sabatti Lisa A Croen Brad P Dispensa Mary Henderson Carlos Iribarren Eric Jorgenson Lawrence H Kushi Dana Ludwig Diane Olberg Charles P Quesenberry Sarah Rowell Marianne Sadler Lori C Sakoda Stanley Sciortino Ling Shen David Smethurst Carol P Somkin Stephen K Van Den Eeden Lawrence Walter Rachel A Whitmer Pui-Yan Kwok Catherine Schaefer Neil Risch

Using genome-wide genotypes, we characterized the genetic structure of 103,006 participants in the Kaiser Permanente Northern California multi-ethnic Genetic Epidemiology Research on Adult Health and Aging Cohort and analyzed the relationship to self-reported race/ethnicity. Participants endorsed any of 23 race/ethnicity/nationality categories, which were collapsed into seven major race/ethnici...

2013
Priya Moorjani Nick Patterson Po-Ru Loh Mark Lipson Péter Kisfali Bela I. Melegh Michael Bonin Ľudevít Kádaši Olaf Rieß Bonnie Berger David Reich Béla Melegh

The Roma people, living throughout Europe and West Asia, are a diverse population linked by the Romani language and culture. Previous linguistic and genetic studies have suggested that the Roma migrated into Europe from South Asia about 1,000-1,500 years ago. Genetic inferences about Roma history have mostly focused on the Y chromosome and mitochondrial DNA. To explore what additional informati...

2010
Salvador Contreras

Abstract Quantitative work has demonstrated that among immigrant groups in the United States there are quite varied differences in inter-generational outcomes. This paper presents a qualitative examination as to what produces these differences. The underlying theory is that educational outcome differences are due to exogenous shocks that alter household educational investment choices. This pape...

Journal: :Journal of lipid research 2008
Clive R Pullinger Bradley E Aouizerat Irina Movsesyan Vincent Durlach Eric J Sijbrands Katsuyuki Nakajima Annie Poon Geesje M Dallinga-Thie Hiroaki Hattori Lauri L Green Pui-Yan Kwok Richard J Havel Philip H Frost Mary J Malloy John P Kane

Apolipoprotein A-V (apoA-V) is an important regulator of plasma levels of triglyceride (TG) in mice. In humans, APOA5 genetic variation is associated with TG in several populations. In this study, we determined the effects of the p.185Gly>Cys (c.553G>T; rs2075291) polymorphism on plasma TG levels in subjects of Chinese ancestry living in the United States and in a group of non-Chinese Asian anc...

2016
Kuan Sun Yi Ye Tao Luo Yiping Hou

Ancestry inference is of great interest in diverse areas of scientific researches, including the forensic biology, medical genetics and anthropology. Various methods have been published for distinguishing populations. However, few reports refer to sub-populations (like ethnic groups) within Asian populations for the limitation of markers. Several InDel loci located very tightly in physical posi...

2016
Jingya Qiu Jason H. Moore Christian Darabos

Genome-wide association studies (GWAS) have led to the discovery of over 200 single nucleotide polymorphisms (SNPs) associated with type 2 diabetes mellitus (T2DM). Additionally, East Asians develop T2DM at a higher rate, younger age, and lower body mass index than their European ancestry counterparts. The reason behind this occurrence remains elusive. With comprehensive searches through the Na...

Journal: :British Journal of Cancer 2010

a-tocopheryl succinate 1224 a-trinositol 833 ABCG2 1276 acoustic neuroma 1654 acquired resistance 383 actomyosin contractility 392 ADCC 520 adenocarcinoma 1692 adenoma 765 adenovirus 796 adipocytes 403 adipose tissue 1541 AdnaTest 276 advanced breast cancer 1341 advanced disease 1687 advanced gastric cancer 475 advanced oesophageal cancer 475 adverse events 80 AEE788 1235 AFP 748 Africa 957 Afr...

Journal: :Nature communications 2016
Qiao Fan Virginie J M Verhoeven Robert Wojciechowski Veluchamy A Barathi Pirro G Hysi Jeremy A Guggenheim René Höhn Veronique Vitart Anthony P Khawaja Kenji Yamashiro S Mohsen Hosseini Terho Lehtimäki Yi Lu Toomas Haller Jing Xie Cécile Delcourt Mario Pirastu Juho Wedenoja Puya Gharahkhani Cristina Venturini Masahiro Miyake Alex W Hewitt Xiaobo Guo Johanna Mazur Jenifer E Huffman Katie M Williams Ozren Polasek Harry Campbell Igor Rudan Zoran Vatavuk James F Wilson Peter K Joshi George McMahon Beate St Pourcain David M Evans Claire L Simpson Tae-Hwi Schwantes-An Robert P Igo Alireza Mirshahi Audrey Cougnard-Gregoire Céline Bellenguez Maria Blettner Olli Raitakari Mika Kähönen Ilkka Seppala Tanja Zeller Thomas Meitinger Janina S Ried Christian Gieger Laura Portas Elisabeth M van Leeuwen Najaf Amin André G Uitterlinden Fernando Rivadeneira Albert Hofman Johannes R Vingerling Ya Xing Wang Xu Wang Eileen Tai-Hui Boh M Kamran Ikram Charumathi Sabanayagam Preeti Gupta Vincent Tan Lei Zhou Candice E H Ho Wan'e Lim Roger W Beuerman Rosalynn Siantar E-Shyong Tai Eranga Vithana Evelin Mihailov Chiea-Chuen Khor Caroline Hayward Robert N Luben Paul J Foster Barbara E K Klein Ronald Klein Hoi-Suen Wong Paul Mitchell Andres Metspalu Tin Aung Terri L Young Mingguang He Olavi Pärssinen Cornelia M van Duijn Jie Jin Wang Cathy Williams Jost B Jonas Yik-Ying Teo David A Mackey Konrad Oexle Nagahisa Yoshimura Andrew D Paterson Norbert Pfeiffer Tien-Yin Wong Paul N Baird Dwight Stambolian Joan E Bailey Wilson Ching-Yu Cheng Christopher J Hammond Caroline C W Klaver Seang-Mei Saw Jugnoo S Rahi Jean-François Korobelnik John P Kemp Nicholas J Timpson George Davey Smith Jamie E Craig Kathryn P Burdon Rhys D Fogarty Sudha K Iyengar Emily Chew Sarayut Janmahasatian Nicholas G Martin Stuart MacGregor Liang Xu Maria Schache Vinay Nangia Songhomitra Panda-Jonas Alan F Wright Jeremy R Fondran Jonathan H Lass Sheng Feng Jing Hua Zhao Kay-Tee Khaw Nick J Wareham Taina Rantanen Jaakko Kaprio Chi Pui Pang Li Jia Chen Pancy O Tam Vishal Jhanji Alvin L Young Angela Döring Leslie J Raffel Mary-Frances Cotch Xiaohui Li Shea Ping Yip Maurice K H Yap Ginevra Biino Simona Vaccargiu Maurizio Fossarello Brian Fleck Seyhan Yazar Jan Willem L Tideman Milly Tedja Margaret M Deangelis Margaux Morrison Lindsay Farrer Xiangtian Zhou Wei Chen Nobuhisa Mizuki Akira Meguro Kari Matti Mäkelä

Myopia is the most common human eye disorder and it results from complex genetic and environmental causes. The rapidly increasing prevalence of myopia poses a major public health challenge. Here, the CREAM consortium performs a joint meta-analysis to test single-nucleotide polymorphism (SNP) main effects and SNP × education interaction effects on refractive error in 40,036 adults from 25 studie...

2009
Margaret Ragland Carolyn Hutter Cyrus Zabetian Karen Edwards

The ubiquitin carboxyl-terminal esterase L1 gene, UCHL1, located on chromosome 4p14, has been studied as a potential candidate gene for Parkinson's disease risk. The authors conducted a Human Genome Epidemiology review and meta-analysis of published case-control studies of the UCHL1 S18Y variant and Parkinson's disease in Asian and Caucasian samples. The meta-analysis of studies in populations ...

Journal: :Evolutionary human sciences 2023

Abstract A tripartite structure for the genetic origin of Japanese populations states that present-day are descended from three main ancestors: 1) indigenous Jomon hunter-gatherers, 2) a Northeast Asian component arrived during agrarian Yayoi period, and 3) major influx East ancestry in imperial Kofun period. However, heterogeneity observed different regions archipelago highlights need to asses...

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