Detailed descriptions of five species of the lichen genus Canoparmelia Elix & Hale. are presented. Until now, three species of the genus Canoparmelia, including C. apata (Krempelh.) Elix & Hale, C. owariensis (Asah.) Elix, and C. texana (Tuck.) Elix & Hale have been reported in South Korea. Canoparmelia carneopruinata (Zahlbr.) Elix & Hale, C. crozalsiana (de Lesd.) Elix & Hale, and C. ecaperat...

The discovery of tissue plasminogen activator to treat acute stroke is a success story of research on preventing brain injury following transient cerebral ischemia (TGI). That this discovery depended upon development of embolic animal model reiterates that proper stroke modeling is the key to develop new treatments. In contrast to TGI, despite extensive research, prevention or treatment of brai...

A major challenge of assisted reproduction technologies (ARTs) is to mimic the natural environment required to sustain oocyte and embryo survival. Herein, we show that the ceramide-metabolizing enzyme, acid ceramidase (AC), is expressed in human cumulus cells and follicular fluid, essential components of this environment, and that the levels of this enzyme are positively correlated with the qua...

One third of patients with aneurysmal subarachnoid haemorrhage (ASAH) present with headache only. A prompt diagnosis is crucial, but these patients must be distinguished from patients with non-haemorrhagic benign thunderclap headache (BTH). The headache characteristics and associated features at onset in subarachnoid haemorrhage and benign thunderclap headache were studied to delineate the rang...

Abstract Background Increased Epicardial Adipose Tissue (EAT) volume has been associated with increased risk of CAD in people living HIV (PLWH). However, the underlying mechanisms remain unknown. Purpose We conducted PIECVIH study to compare EAT properties relation between PLWH and HIV-negative patients, all undergoing coronary artery bypass graft (CABG). Methods The is a cross sectional prospe...

Background Farber disease is frequently misdiagnosed as polyarticular juvenile idiopathic arthritis or seronegative rheumatoid which leads to a delay in diagnosis for many patients. an ultra-rare lysosomal storage caused by mutations the ASAH1 gene. The resulting deficiency of acid ceramidase enzyme accumulation pro-inflammatory and pro-apoptotic sphingolipid ceramide. Accumulation ceramide thr...

Methods Patients with aSAH and occluded aneurysm who developed clinical signs of DCI were randomised to either induced hypertension or no induced hypertension. Hypertension was induced with norepinephrine. Cerebral perfusion was assessed with CTP as CBF (ml/100g/s) in predefined regions (ROIs) on two time points: CTP1) at time of clinical deterioration and CTP2) 24 36 hours after randomisation....