نتایج جستجو برای: as pro
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Background: The p53 tumor suppressor gene plays important roles in genomic stability. Several reports have noted racial differences in the prevalence of p53 genotypes at the codon 72 in patients with endometriosis.To study the association of endometriosis with p53 codon 72 polymorphism in the population of Isfahan. Materials and Methods: We undertook a case–control study to examine the possible...
Background N-terminal pro–B-type natriuretic peptide (NT-proBNP) is a marker to evaluate the cardiac involvement in thalassemia. We aimed to evaluate conventional and tissue Doppler echocardiography findings and its relation to plasma NT-pro BNP, Ferritin and Iron levels in beta-thalassemia patients. Materials and Methods This study performed on 164 participants equal of major beta- thalassemi...
thrombin is a multifunctional enzyme which has key roles in coagulation cascade and inflammatory events. the pro-inflammatory functions of thrombin occur by different mechanisms including increasing mast cell degranulation, up-regulating the expression of cell adhesion molecules (cams) and promoting the secretion of inflammatory chemokines and cytokines. dysregulated signaling functions of thro...
evaluation of p53 codon 72 polymorphism in adenocarcinoma of the colon and rectum in guilan province
background : colorectal cancer is the second cause of mortality in developed countries. the p53gene and some of it's polymorphisms are among the causes for cancer development.the purpose of this study is to evaluate the relationship between the p53 codon 72 polymorphism in colorectal adenocarcinoma specimens compared with controls. materials and methods : we performed a case-control study among...
background: acute respiratory distress (ard) is a critical respiratory failure due to lung injury of neonates leading to the clinical appearance of poor lung compliance. the aimed of the study was to evaluate the diagnostic values in differentiating respiratory from heart diseases with using of n-terminal pro brain natriuretic peptide (nt-pro bnp) and atrial natriuretic peptide(anp) in neonates...
Background and Aim: A single nucleotide polymorphism at codon 72 of the p53 gene alters the p53 protein structure and affects its activity. This polymorphism depends on geographic regions and race. Also its association with some cancers has been reported. The aim of this study was to investigate this polymorphism in well differentiated oral SCC and normal population in the city of Isfahan. Mat...
Introduction: The aim of this study was to assess the relationship between serum level of aminoterminal pro B-type natriuretic peptide and prognosis in patients with respiratory distress in emergency ward of Rasoul Akram Hospital(Tehran, Iran). Methods: In this cohort study which was conducted in the emergency ward of Rasoul Akram hospital, after considering inclusion ad exclusion criteria, 6...
مقدمه: امروزه یکی مهم ترین مشکلات بیماران تالاسمی ماژور، اضافه بار آهن و هموسیدروز می باشد، که پیامد آن رسوب آهن در بافت میوکارد و وقوع کاردیومیوپاتی ناشی از هرماکروماتیز است. هدف از انجام پژوهش حاضر، تعیین تأثیر هشت هفته تمرین مقاومتی - استقامتی هم زمان بر مقادیر سرمی nt-pro bnp و فریتین، بیماران بتا تالاسمی ماژور بود. روش کار: بدین منظور 18 نفر از بیماران بتاتالاسمی ماژور مرکز بیماری های خاص ...
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