Ribosomal DNA (rDNA) replication origins of Saccharomyces cerevisiae are known to function inefficiently, both in the context of the tandem rDNA repeats in the chromosome and as single copy autonomously replicating sequences (ARSs) in plasmids. Here we examined components of the rDNA ARS that might contribute to inefficient extrachromosomal replication. Like the efficient H4 ARS, the rDNA ARS r...

BACKGROUND Prospectively and systematically collected data on frequency and spectrum of unexpected clinical manifestations during primary human immunodeficiency virus (HIV) infection (PHI) have not been published. METHODS We prospectively enrolled 290 patients with documented PHI in the Zurich Primary HIV Infection Study. Typical acute retroviral syndrome (ARS) was defined as fever plus at le...

We give a short answer to the question in the title: dendrits. Precisely we show that the C∗-algebra C(X) of all complex-valued continuous functions on a compactum X is projective in the category C of all (not necessarily commutative) unital C∗-algebras if and only if X is an absolute retract of dimension dimX ≤ 1 or, equivalently, that X is a dendrit.

The preparation of redox-active coatings is a key step in fabricating electrochemical biosensors. To this goal, a variety of coating materials have been used in combination with redox-active compounds. In this study, alizarin red S (ARS) was confined in layer-by-layer (LbL) films composed of poly(ethyleneimine) (PEI) and carboxymethylcellulose (CMC) to study the redox properties. A gold (Au) di...

We evaluated the effectiveness of Streptococcus iniae vaccines prepared from formalin-killed Ž . cells and concentrated extracellular products greater than 2 kDa of a single isolate of S. iniae Ž . ARS-10 and a combination of ARS-10qARS-60 S. iniae isolates in tilapia, Oreochromis niloticus, for the prevention of streptococcal disease. Two routes of administration, intraperitoneal Ž . Ž . i.p. ...

We investigated the influence of the macromolecular form of an epitope on the structure of antibody variable and constant regions expressed by the B cell population participating in an immune response to that epitope. Hybridomas were constructed from strain A/J mice undergoing either primary or secondary immune responses to p-azophenylarsonate conjugated to Brucella abortus (Ars-Bruc). We deter...