نتایج جستجو برای: arrhythmogenicity

تعداد نتایج: 246  

2009
Hideyuki Kinoshita Koichiro Kuwahara Yuji Arai Yoshihiro Kuwabara Shinji Yasuno Yasuaki Nakagawa Michio Nakanishi Masao Murakami Kenji Ueshima Kazuwa Nakao

Background—Pharmacological interventions for prevention of sudden arrhythmic death in patients with chronic heart failure remain limited. Accumulating evidence suggests increased ventricular expression of T-type Ca 2ϩ channels contributes to the progression of heart failure. The ability of T-type Ca 2ϩ channel blockade to prevent lethal arrhythmias associated with heart failure has never been t...

2016
Gary Tse Vivian Tse Jie Ming Yeo Bing Sun Alena Talkachova

Acute effects of heptanol (0.1 to 2 mM) on atrial electrophysiology were explored in Langendorff-perfused mouse hearts. Left atrial bipolar electrogram or monophasic action potential recordings were obtained during right atrial stimulation. Regular pacing at 8 Hz elicited atrial activity in 11 out of 11 hearts without inducing atrial arrhythmias. Programmed electrical stimulation using a S1S2 p...

2015
Sandhya Manohar Binaya Raman Dahal Bernard Gitler

Brugada syndrome is increasingly recognized as a cause of sudden cardiac death. Many of these patients do not get diagnosed due its dynamic and often hidden nature. We have come a long way in understanding the disease process, and its electrophysiology appears to be intimately linked with sodium channel mutations or disorders. The cardiac rhythm in these patients can deteriorate into fatal vent...

2017
Cristiane Alves da Silva Menezes Ana Thereza Chaves Manoel Otávio da Costa Rocha

Chagas disease is a protozoonoses caused by Trypanosoma cruzi. After chronification, human infection may present with several clinical manifestations, ranging from asymptomatic disease to severe cardiomyopathy. Currently, it is estimated that about 7 million people are infected, of which approximately 30% develop heart disease. Chronic Chagas cardiomyopathy (CCC) is the main cause of morbidity ...

2008
Anabel Varela-Carver Husein Salem Kenta Yashiro Magdi H. Yacoub Steven R. Coppen Satsuki Fukushima Yasunori Shintani

Copyright © 2008 American Heart Association. All rights reserved. Print ISSN: 0009-7322. Online 72514 Circulation is published by the American Heart Association. 7272 Greenville Avenue, Dallas, TX DOI: 10.1161/CIRCULATIONAHA.107.779629 2008;118;S138-S144 Circulation Suzuki Anabel Varela-Carver, Husein Salem, Kenta Yashiro, Magdi H. Yacoub and Ken Steven R. Coppen, Satsuki Fukushima, Yasunori Sh...

2012
Bobby Heydari Shuaib Abdullah Evan Appelbaum Damien Mandry Ron Blankstein Yucheng Chen Jiazuo H Feng Karl-Philipp Kienle Elliott Antman Heidi S Lumish Sanjeev Francis Henry Gewirtz Udo Hoffmann Daniel Forman Lahn Fendelander Roger Plaisted Rob J van der Geest Michael Jerosch-Herold Raymond Kwong

CMR quantification of infarct tissue heterogeneity and remote myocardial fibrotic burden during convalescent phase following acute myocardial infarction (MI) provided strong and complementary evidence of ventricular arrhythmogenicity from quantitative microvolt T-wave alternans testing (the NHLBI PROSPECT-CMR study) Bobby Heydari, Shuaib Abdullah, Evan Appelbaum, Damien Mandry, Ron Blankstein, ...

2011
Bulent Koca Ozgur Kasapcopur Suleyman Bakari Emre Celik Ayse Guler Eroglu Levent Saltik Funda Oztunc Ozden Calay

Background and aim Juvenile idiopathic arthritis (JIA) is the most common rheumatologic disorder of childhood. Cardiac involvement as pericarditis, myocarditis and valvular disease is common in JIA (JIA). There are, however, few descriptions concerning systolic and diastolic functions of the left ventricle (LV) in children with JIA. P wave dispersion (PWD) is a sign for the prediction of atrial...

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