We showed that aristolochic acid toxin (ARI) and its fluorescent analogue form inclusion complexes with various cyclodextrins (CDs), including the clinically used γ-CD: Sugammadex. The binding affinity of ARI towards CDs varied on a CD size rim modifications, whereby stability ARI/Sugammadex complex was 2-fold greater than to serum albumin (BSA), blood protein well-known as transporter small mo...

BACKGROUND AND OBJECTIVE Clinical guidelines discourage antibiotic prescribing for many acute respiratory infections (ARIs), especially for non-antibiotic appropriate diagnoses. Electronic health record (EHR)-based clinical decision support has the potential to improve antibiotic prescribing for ARIs. METHODS We randomly assigned 27 primary care clinics to receive an EHR-integrated, documenta...

Acute respiratory tract infections (ARI) are a major burden in pediatric long-term care. We analyzed the financial impact of ARI in 2012-2013. Costs associated with ARI during the respiratory viral season were ten times greater than during the non-respiratory viral season, $31 224 and $3242 per 1000 patient-days, respectively (P < 0·001). ARI are burdensome for pediatric long-term care faciliti...

OBJECTIVE To investigate the relationship between vitamin A deficiency (VAD), vitamin E deficiency (VED) and infectious diseases. PATIENTS AND METHODS We chose 684 cases of healthy children age 5 months-12 years from our hospital, measured their VA, VE from vein under the light proof condition with high-pressure liquid chromatography. Thereafter, the children who get the acute respiratory tra...

Background Acute respiratory tract infection (ARI) remains the major cause of child mortality in Sub-Saharan Africa. Various factors are associated with its occurrence and vary by context. However, available large-scale, population-based data are not fully exploited to identify locally relevant risk factors. The objective of this study was to identify factors associated with ARI in children und...

abstract background: acute respiratory infections (ari) are the main cause for antibiotic (ab) use in all age groups specially the first two years of life. the local information about the pattern of ab prescription in ari is a necessary part for any program which aims logical use of ab. the current study was designed to find the frequency and types of ab administration for ari in young children...

A prospective cohort study was conducted to estimate the incidence of acute respiratory infections (ARI) among hajjis registered at primary health care centres of Riyadh. Out of 1027 hajjis, 39.8% developed symptoms of ARI. The incidence of ARI was not statistically significantly associated with age, sex, educational status or smoking. The risk of illness was significantly higher among diabetic...

Background Acute respiratory diseases are the most common international human illnesses. Acute respiratory infection (ARI) in under five year old children represent the most common health problem in paediatric practice all over the world. It is reported that all children under five years suffer from 6-8 respiratory infections annually, which represent about 50% of all preschooler illnesses. The...