Despite decades of biomedical advances, the colonization implant devices with bacterial biofilms is still a leading cause failure. Clearly, new strategies and materials that suppress both initial later stage are required in this context. Ideal would be implementation bactericidal functionality implants temporally spatially triggered an autonomous fashion at infection site. Herein, fabrication v...

Aqueous solutions of various types honey as a source reducing sugars – glucose and fructose, were used to accelerate or control activators regeneration by electron transfer atom radical polymerization (ARGET ATRP) in homogeneous heterogeneous environment. The aqueous alcoholic-aqueous solution was applied for the hydrophilic methacrylates i.e. 2-(dimethylamino)ethyl methacrylate (DMAEMA), glyci...

Amphiphilic A2(BC)2 miktoarm star polymers [poly(ϵ-caprolactone)]2-[poly(2-(diethylamino)ethyl methacrylate)-b- poly(poly(ethylene glycol) methyl ether methacrylate)]2 [(PCL)2(PDEA-b-PPEGMA)2] were developed by a combination of ring opening polymerization (ROP) and continuous activators regenerated by electron transfer atom transfer radical polymerization (ARGET ATRP). The critical micelle conc...

A new peptide-based system supported on copolymer brushes grafted from gold sensors and with resistance to nonspecific adsorption is reported for selective binding of human immunoglobulin G (IgG). A random copolymer rich in primary amines, poly(2-aminoethyl methacrylate hydrochloride-co-2-hydroxyethyl methacrylate) (poly(AMA-co-HEMA)) was first grafted from initiator-coated gold substrates via ...

As inspired by the Dot blot analysis, a well known technique in molecular biology and genetics for detecting biomolecules, a new paper-based platform for colorimetric detection of specific DNA sequences employing peptide nucleic acid (PNA) as a probe has been developed. In this particular study, a pyrrolidinyl PNA bearing a conformationally rigid d-prolyl-2-aminocyclopentanecarboxylic acid back...

Amphiphilic tetrafluorostyrene monomers (EFS8) carrying in the para position an oligoethylene glycol chain containing 8 oxyethylenic units on average were synthesized and used for preparation via activator regenerated by electron transfer atom radical polymerization (ARGET-ATRP) of corresponding amphiphilic homopolymers (pEFS8-x) with different degrees (x = 26 46). Combining light transmittance...

This Perspective presents recent advances in macromolecular engineering enabled by ATRP. They include the fundamental mechanistic and synthetic features of ATRP with emphasis on various catalytic/initiation systems that use parts-per-million concentrations of Cu catalysts and can be run in environmentally friendly media, e.g., water. The roles of the major components of ATRP--monomers, initiato...

Controlled radical polymerization has proven to be a viable route to obtain polymers with narrow polydispersities (PDI’s) and controlled molecular weights under simple reaction conditions. It also offers control over the chain‐ends of the synthesized polymer. Atom transfer radical polymerization (ATRP) is the most studied and utilized of these techniques. In this study ATRP has ...