PURPOSE The dose values computed with the treatment planning system and the in vivo dose measurements with semiconductor detectors in rectum during the high dose rate brachytherapy treatment fraction of the cervix carcinoma are occasionally significantly different. We've investigated the consistency of the Fletcher-Suit applicator geometry and the in vivo rectal probe's position stability durin...

*Corresponding author: Dr. Mohammad Amin Mosleh-Shirazi, Department of Radiotherapy and Oncology, Shiraz University of Medical Sciences, Shiraz, Iran. Fax: +98 711 6474320 E-mail: [email protected] Background: The dose rate distribution delivered by a low dose rate 137Cs pellet source, a spherical source used within the source trains of the Selectron gynecological brachytherapy system, was inv...

PURPOSE We present a framework, in which we compare a conventional standard dose of 50 Gy in 25 fractions with accelerated partial breast irradiation (APBI) using electronic brachytherapy (eBT). We discuss how radiobiological modelling enables us to establish a framework, within which we can compare external beam radiotherapy (EBRT). This leads to a determination of the shell of isoeffect in br...

High temperature ultrasound thermal therapy using interstitial and external approaches is becoming increasingly acceptable as a minimally invasive clinical treatment for cancerous and benign disease. The diameter of an interstitial applicator can influence its clinical practicality and effectiveness as well as application site. The purpose of this study was to determine whether the use of large...

BACKGROUND AND OBJECTIVES Many studies have investigated the application of micro-insulated needles with radio frequency (RF) to treat acne in humans; however, the use of a micro-insulated needle RF applicator has not yet been studied in an animal model. The purpose of this study was to evaluate the effectiveness of a micro-insulated needle RF applicator in a rabbit ear acne (REA) model. STUD...

Introduction: The use of electrons in the electron therapy to destroy tumoral tissue is dedicated significant contribution of different methods of radiation therapy. Scattered radiation due to exited electrons of the applicator affect the dose out of the field in the patient's normal tissue. The aim of this study is to determine the peripheral dose outside the applicator in the...

The treatment of large tumors such as sarcomas with intra-operative radiotherapy using a Mobetron is often complicated because of the limited field size of the primary collimator and the available applicators (max Ø100 mm). To circumvent this limitation a prototype rectangular applicator of 80 x 150 mm(2) was designed and built featuring an additional scattering foil located at the top of the a...

Standard applicators for cervix cancer brachytherapy (BT) do not always enable a sufficient radiation dose coverage of the target structure (HR-CTV). The aim of this study was to develop methodology for building models of the BT target from a cohort of cervix cancer patients, which would enable BT applicator testing. In this paper we propose two model types, a spatial distribution model and a p...

We investigate the feasibility of trans-rectal optical tomography of the prostate using an endo-rectal near-infrared (NIR) applicator that is to be integrated with a trans-rectal ultrasound (TRUS) probe. Integration with TRUS ensures accurate endo-rectal positioning of the NIR applicator and the utility of using TRUS spatial prior information to guide NIR image reconstruction. The prostate NIR ...

Monte Carlo calculations of the absorbed dose at various points of a brachytherapy anthropomorphic phantom are presented. The phantom walls and internal structures are made of polymethylmethacrylate and its external shape was taken from a female Alderson phantom. A complete Fletcher-Green type applicator with the uterine tandem was fixed at the bottom of the phantom reproducing a typical geomet...