Congenital leukemia is a rare disease which in clinically evident at birth or apparent within the first few weeks of life; The disease is more common in infants with downs syndrome.  We present a case of combined mongolism and congenital leukemia and reviewe some aspect of the disease. 

Apparent life-threatening events account for 0.6% to 0.8% of all emergency department visits for children aged < 1 year. Risk factors for serious underlying pathology in a well-appearing infant have been identified as prematurity, underlying medical conditions, age < 60 days (considered controversial), suspicion of child abuse, possible seizure activity, and recurrent apparent life-threatening ...

Many physicians have received a frantic call from anxious parents stating that their child had stopped breathing, become limp, or turned blue but then had recovered quickly. An apparent life-threatening event (ALTE) is defined as "an episode that is frightening to the observer, and is characterized by some combination of apnea, color change, marked change in muscle tone, choking, gagging, or co...

PURPOSE An apparent life-threatening event (ALTE) refers to the sudden occurrence in an infant of a breathing abnormality, color change, or alteration in muscle tone or mental status. The finding of retinal hemorrhage in an infant who has experienced an ALTE strongly suggests the possibility of shaken baby syndrome. Previous ALTE studies have reported the frequency of this specific ocular abnor...

OBJECTIVE To identify potential risk factors for unexpected sudden infant deaths (SID) and severe apparent life-threatening events (S-ALTE) within 24 h of birth. DESIGN Case-control study embedded in an epidemiological survey over a 2-year period. PATIENTS AND METHODS Throughout 2009, every paediatric department in Germany was asked to report cases of unexplained SID or S-ALTE in term infan...