BACKGROUND This study aims to investigate the biocompatibility and in vivo osteogenic capability of the novel bone tissue engineering scaffold apatite-wollastonite-magnetic glass ceramic/chitosan (A-W-MGC/CS). METHODS Rabbit bone marrow stromal cells (BMSCs) were transfected with adenovirus-human bone morphogenetic protein-2-green fluorescent protein (Ad-hBMP2-GFP). The transfected BMSCs were...

Glass ionomer cements (GIC) are known as a non-bioactive dental cement. During setting the GIC have an acidic pH, driven by the acrylic acid component. It is a challenge to make GIC alkaline without disturbing its mechanical properties. One strategy was to add slowly reacting systems with an alkaline pH. The aim of the present study is to investigate the possibility of forming a bioactive denta...

In order to improve the chemical stability and modify the biodegradability of bio-glass ceramics materials for certain applications, a correlation between structural and biological properties of bio-glass ceramics is very essential and these properties are found to be greatly dependent on the composition and synthetic parameters of the material. In the present work, an attempt has been made to ...

We have developed a new drug delivery system using porous apatite-wollastonite glass ceramic (A-W GC) to treat osteomyelitis. A-W GC (porosity, 70% and 20% to 30%), or porous hydroxyapatite (HA) blocks (porosity 35% to 48%) used as controls, were soaked in mixtures of two antibiotics, isepamicin sulphate (ISP) and cefmetazole (CMZ) under high vacuum. We evaluated the release concentrations of t...

a day, 5 days a week for 12 months plus 12 months observation, or for a full 24 months) inhalation exposure of wollastonite in rats (McConnell et al, 1991), I was surprised to find the authors of this article reporting pulmonary fibrosis after intratracheal (IT) instillation. I offer the following comments and possible explanation for this unexpected result. It is difficult to determine from th...

This work investigated the pilot scale production of short chain fatty acids (SCFAs) from sewage sludge through alkaline fermentation and the subsequent membrane filtration. Furthermore, the impact of the fermentation liquid on nutrient bioremoval was examined. The addition of wollastonite in the fermenter to buffer the pH affected the composition of the carbon source produced during fermentati...

PURPOSE To review the radiology and histology of synthetic bone grafts resected from patients with recurrent giant cell tumour (GCT) of bone. METHODS 22 patients underwent curettage and grafting for GCT of bone using autogenous cancellous bone mixed with apatite-wollastonite-containing glass ceramic (AWGC), hydroxyapatite (HA), or a mixture of HA and tricalcium phosphate (TCP). Patients were ...

Occurrence of sediments hosted smooth surfaced flat / discoid black and pink coloured bimodal carbonatite bombs, lapillus, pisolites and ashes in semi-unconsolidated conglomerate covering an area of 90 sq.km is reported from Thiruvalangadu (13 o 10’36”N-76 o 44’38”E) area situated 60 km WNW of Chennai. The carbonatite materials are uniformly composed of flow-oriented fine-grained calcites <0.02...

This work focuses on the effect of β-wollastonite percentage with different particle sizes bulk density and weight loss clay-based ceramics. The ceramic bodies were prepared by mixing clay a synthesized (5%, 15%, 25%) using solid slip casting method. (75 µm) (63, 75, 125 mixed fired at 950°C, 1000°C, 1050°C firing temperatures. fabricated material exhibited maximum 2.35 g/cm3 25% content β-woll...