High-precision stepped-heating experiments were performed to better characterize helium diffusion from apatite using Durango fluorapatite as a model system. At temperatures below 265øC, helium diffusion from this apatite is a simple, thermally activated process that is independent of the cumulative fraction of helium released and also of the heating schedule used. Across a factor of -4 in grain...

here we report a novel approach for preparation of a 6-day transdermal drug delivery system (tdds) as treatment for mild to moderate alzheimer’s disease. the spray drying method was used to prepare microparticles containing the anti-alzheimer drug. the content of the drug was determined by high performance liquid chromatography (hplc) method. the morphology and size range of the microparticles ...

Bioactive glass-containing toothpastes for treating dentine hypersensitivity work by precipitating hydroxycarbonate apatite (HCA) onto the tooth surface, but concerns exist over the long-term durability of HCA in the mouth. Fluoride-containing bioactive glasses form fluorapatite (FAp) in physiological solutions, which is more chemically stable against acid attack. The influence of phosphate con...

Bone-like apatite formed on the surface of Ti6Al4V pretreated with NaOH solution after having been immersed in simulated body fluid (SBF), while no apatite formed on the surface of untreated Ti6Al4V. In the present study, electrochemical impedance spectroscopy (EIS) measurement was used to investigate the nucleation and growth of apatite on chemically treated Ti6Al4V immersed in the SBF solutio...

Sediment amendments provide promising strategies of enhancing sequestration of heavy metals and degradation of organic contaminants. The impacts of sediment amendments for metal and organic remediation including apatite, organoclay (and apatite and organoclay in geotextile mats), acetate, and chitin on environmental microbial communities in overlying water and sediment profiles are reported her...

The bioactive glass 45S5 was crystallized to 8-100 vol % of crystals by thermal treatments from 550-680 degrees C. The micro-structure of the glass-ceramics had a very uniform crystal size, ranging from 8 to 20 microns. Fourier-transform infrared (FTIR) spectroscopy was used to determine the rate of hydroxycarbonate apatite (HCA) formation that occurs on bioactive glass and glass-ceramic implan...

Bone morphogenetic proteins (BMPs) need an effective delivery system for efficient bone regeneration. In this study, we evaluated the efficiency of an apatite-coated collagen sponge for the long-term delivery of BMP-2 in a rabbit model of lumbar posterolateral fusion. A total of 15 rabbits, divided into three groups, underwent posterolateral lumbar fusion. The first group (control group) receiv...

A series of Co doped lanthanum silicate apatite-type phases, La9.83Si4.5Co1.5O26, La9.66Si5CoO26, La10Si5CoO26.5 and La8BaCoSi6O26, have been synthesised, and neutron diffraction, EXAFS and XANES used to investigate their structures in detail. All compositions were shown to possess the hexagonal apatite structure, and the results confirmed that cobalt can be doped onto both the La and Si sites ...

The classic biomimetic apatite coating process can be accelerated by first immersing substrates into concentrated simulated body fluid, 5x SBF (SBF1), at 37 degrees C, to form an initial coating of precursor apatite spheres, and subsequently transferring to a second 5x SBF (SBF2) solution which is devoid of crystal growth inhibitors to promote phase transformation of SBF1-derived precursor apat...

In order to elucidate the main factor governing the capacity for apatite formation of titanium (Ti), Ti was exposed to HCl or NaOH solutions with different pH values ranging from approximately 0 to 14 and then heat-treated at 600°C. Apatite formed on the metal surface in a simulated body fluid, when Ti was exposed to solutions with a pH less than 1.1 or higher than 13.6, while no apatite formed...