The authors propose a new strategy of normothermic perfusion for replacement of the aortic arch to avoid the complications of profound hypothermic circulatory arrest. Six patients underwent complete replacement of the aortic arch under normothermia using two pumps for the body (one for the brain and the thoracoabdominal aortic branches) and one for the heart. The surgical procedure was performe...

OBJECTIVES To elucidate the role of fluid mechanical factors in the localized genesis and development of atherosclerotic lesions in man. METHODS Flow patterns and preferred sites of atherosclerotic lesions in the human aortic arch were studied in detail using isolated transparent aortic trees prepared from humans postmortem and by means of flow visualization of tracer polystyrene microspheres...

A hybrid approach, combining open and endovascular procedures, may be a less invasive substitute to correct aortic arch pathologies in high-risk patients. We describe an 82-year-old male patient with an atherosclerotic aortic arch aneurysm, which was treated with proximal transposition of all arch branches and endovascular aortic arch repair. During the left common carotid artery reconstruction...

Figure 1: CT images. (A) Preoperative three-dimensional CT image. Dextrocardia was observed preoperatively. The branches of the aortic arch were mirror-image reversed. (B) Postoperative three-dimensional CT image. Reconstructed aorta and branches were also mirror-image reversed. RV: right ventricle; Ao: aorta; BCA: brachiocephalic artery; Rt.SCA: right subclavian artery; Rt.CCA: right common ca...

Pulseless disease or Takayashu's disease is a rare condition characterized by the completc, or almost complete, absence of the arterial pulsation in the upper extremities, and usually in the head and neck, due to an obliterative process in the great branches of the aortic arch. Although wellknown by Japanese writers, it has received little attention in this country. The earliest recorded case w...

Although the murine thoracic aorta and its main branches are widely studied to gain more insight into the pathogenesis of human vascular diseases, detailed anatomical data on the murine aorta are sparse. Moreover, comparative studies between mice and men focusing on the topography and geometry of the heart and aorta are lacking. As this hampers the validation of murine vascular models, the bran...

Absolute contraindications to percutaneous tracheostomy due to anomaly of aortic arch branches origin and running A 77-year-old patient required percutaneous tracheost-omy. A first clinical evaluation showed a pulsating mass in the suprasternal region. Computed tomography (CT) revealed the presence of anomaly of the aortic arch branches (Fig. 1). We did not perform any type of tracheostomy due ...

A three-dimensional computer model of human aortic arch with three branches is reproduced to study the pulsatile blood flow with Finite Element Method. In specific, the focus is on variation of wall shear stress, which plays an important role in the localization and development of atherosclerotic plaques. Pulsatile pressure pulse is used as boundary condition to avoid flow entry development, an...