Tuberculosis therapy utilizes drugs that while effective cause treatment-related toxicity. Modulation of antitubercular drugs-induced toxicity by methionine and vitamin B-complex in patients was evaluated. 285 treatment-naïve tuberculosis patients at the Chest Clinics of Infectious Diseases Hospital, Yaba and General Hospital, Lagos in Lagos, Nigeria was prospectively recruited and allotted int...

Splenic tuberculosis per se in an immunocompetent individual is very rare. We came across a case of a middle aged, immunocompetent female who presented with fever, weight loss, and left hypochondriac pain. She had earlier been treated for pulmonary tuberculosis one year back and declared cured after six months of antitubercular chemotherapy. Ultrasonography and computed tomography of abdomen re...

Tuberculosis is a great masquerader presenting in varied forms and in atypical locations. The myriad presentations of tuberculosis may complicate its diagnosis. We present two cases of acromioclavicular joint tuberculosis treated with a regimen of antitubercular drugs for 18 months leading to a complete resolution of symptoms.

Translocase I inhibitor compounds derived from capuramycin demonstrated rapid bactericidal activity against several different mycobacterial species. SQ641 was the most active of the compounds, with a MIC of 0.12 to 8 microg/ml, a postantibiotic effect of 55 h, and interesting synergistic effects with other antitubercular drugs.

A young female presented with complaint of swelling of the parotid region for one year. She was diagnosed as a case of primary tubercular parotiditis. The diagnosis was confirmed by fine needle aspiration cytology. She was managed with antitubercular drugs. After completing the course the swelling resolved completely and there was no recurrence.