BACKGROUND The effects of in utero exposure to atypical antipsychotics on infant birth weight are unknown. AIMS To determine whether atypical and typical antipsychotics differ in their effects on birth weight after maternal exposure during pregnancy. METHOD Prospective data on gestational age and birth weight collected by the National Teratology Information Service for infants exposed to ty...

AIMS AND METHOD To establish if participants with schizophrenia receiving depot antipsychotics had less insight than similar participants receiving oral atypical antipsychotics.We assessed the difference between these two groups. RESULTS Participants on oral antipsychotics had greater insight than those on depot antipsychotics (ITAQ, P=0.01). In the multiple regression analysis, only receiving ...

Introduction Atypical antipsychotics have largely replaced typical antipsychotics in clinical practice due to their perceived superiority in efficacy and lower risk of neurological adverse effects, which is believed to result in improved compliance. In fact, many treatment algorithms recommend the use of atypical antipsychotics as the only first-line medication treatment option. However, the Cl...

OBJECTIVE To develop an evidence base for recommendations on the use of atypical antipsychotics for patients with schizophrenia. DESIGN Systematic overview and meta-regression analyses of randomised controlled trials, as a basis for formal development of guidelines. SUBJECTS 12 649 patients in 52 randomised trials comparing atypical antipsychotics (amisulpride, clozapine, olanzapine, quetia...

Abstract Use of psychotropic medicines such as antipsychotics, antidepressants, and anxiolytics is common in children with autism spectrum disorder (ASD); however, very little known about medicine use adults ASD. This pilot project aimed to describe Australian We conducted a retrospective analysis mental health care plan records for confirmed diagnosis ASD from single metropolitan psychology pr...

CONTEXT The role of antipsychotics as adjuvant analgesics is a subject of long-standing controversy. Antipsychotics have been used to treat chronic pain (e.g., chronic headache, fibromyalgia, and painful diabetic neuropathy). With atypical antipsychotics, a new class of antipsychotics, with fewer extrapyramidal side effects and additional benefits, may be available. OBJECTIVES This review aim...

The use of antipsychotics for the treatment of behavioural and psychological symptoms of dementia (BPSD) is controversial. Antipsychotics cause harm and evidence-based guidelines advise against their use. We argue that antipsychotics may be justified using a palliative model: by reducing severe distress in those whose life expectancy is short.

Second generation antipsychotics are associated with weight gain and other metabolic side effects (1). Among the atypical antipsychotics, treatment with olanzapine has been found to worsen the lipid profile (2). Atypical antipsychotics also increase the risk of developing metabolic syndrome (3, 4). The baseline prevalence of diabetes maybe two to three folds higher in patients with schizophreni...

BACKGROUND Several clinical practice guidelines suggest using atypical over typical antipsychotics in patients diagnosed with schizophrenia. Nevertheless, cost-containment policy urged restricting usage of atypical antipsychotics and switching from atypical to typical antipsychotics. OBJECTIVE This study aimed to evaluate clinical and economic impacts of switching from atypical to typical ant...