BACKGROUND Treatment-refractory visceral leishmaniasis (VL) has become an important problem in many countries. OBJECTIVES We evaluated the antimony-resistance mechanisms of Leishmania infantum isolated from VL patients refractory or responsive to treatment with pentavalent antimony. METHODS Strains isolated from antimony-refractory patients (in vitro antimony-resistant isolates) and antimony-re...

Until ten years ago the grids of lead-acid batteries were usually made of lead-antimony alloys containing 5-11 wt. % antimony. The necessary mechanical strength and castability are easily achieved with this content of antimony. However, the unavoidable corrosion of the positive grid liberates antimony from the grid, which proves to be both unfavorable as well as unfavorable with respect to batt...

This study investigated antimony exposure among employees in industries in Taiwan and evaluated whether their immunologic markers were associated with antimony exposure. We recruited 91 male workers and 42 male office administrators from 2 glass manufacturing plants, 1 antimony trioxide manufacturing plants, and 2 engineering plastic manufacturing plants. Air samples were collected at worksites...

Antimony oxides, in combination with halogens, have been used as flame retardants in textiles since the 1960s. Uniforms made from fabric containing antimony are common among the estimated 1.1 million firefighters in the United States. In October 2008, CDC received a report from the fire chief of a fire department in Florida (fire department A) regarding an outbreak of antimony toxicity among 30...

This study estimated the dietary exposure to antimony of secondary school students in Hong Kong and assessed the associated health risks. Dietary exposure to antimony was estimated using the local food consumption data obtained from secondary school students in 2000 and the concentrations of antimony in food samples taken from the local market. Laboratory analysis for antimony was conducted by ...

Antimonial-containing drugs are the first line of treatment against Leishmaniasis. Resistance to antimonials in Leishmania is proposed to be due to reduced uptake of trivalent antimony (SbIII) through the aquaglyceroporin (AQP1). We investigated the uptake of SbIII and involvement of aquaglyceroporin in developing antimony resistance phenotype in Leishmania donovani clinical isolates. SbIII acc...

Antimony (Sb) is a toxic metalloid that occurs widely at trace concentrations in soil, aquatic systems, and the atmosphere. Nowadays, with the development of its new industrial applications and the corresponding expansion of antimony mining activities, the phenomenon of antimony pollution has become an increasingly serious concern. In recent years, research interest in Sb has been growing and r...

introduction: lymphoscintigraphy is imaging of the lymphatic system and has been integrated into the sentinel node mapping procedures. lymphoscintigraphy usually encompasses early or delayed static images. however, immediate dynamic imaging of the lymphatic basins and tumors has also been used as an adjunct lymphoscintigraphy imaging. the aim of this study was to assess the role of early dynami...