نتایج جستجو برای: antihelmintic activity
تعداد نتایج: 1134393 فیلتر نتایج به سال:
Helminthes infections are the most common health problems in India, in developing countries they pose a large treat to public. These infections can affect most population in endemic areas with major economic and social consequences. The miswak is a natural toothbrush made from the twigs of the Salvadora persica (Salvadoraceae). Miswak prevents tooth decay, eliminating toothaches and halt furthe...
Background: Ethnobotanical investigations conducted in Turkey demonstrated that Jasminum fruticans L. extract and fruit juice had been used against parasites animals. In this study, the possible antihelmintic activity of various J. extracts contributing to its traditional use, was relatively assessed. addition, antioxidant potentials phytochemical composition were investigated since there is a ...
WNT signaling plays a key role in the self-renewal of tumor initiation cells (TICs). In this study, we used pyrvinium pamoate (PP), an FDA-approved antihelmintic drug that inhibits WNT signaling, to test whether pharmacologic inhibition of WNT signaling can specifically target TICs of aggressive breast cancer cells. SUM-149, an inflammatory breast cancer cell line, and SUM-159, a metaplastic ba...
The hedgehog (Hh) signaling pathway is activated in many types of cancer and therefore presents an attractive target for new anticancer agents. Here, we show that mebendazole, a benzamidazole with a long history of safe use against nematode infestations and hydatid disease, potently inhibited Hh signaling and slowed the growth of Hh-driven human medulloblastoma cells at clinically attainable co...
جهت بهینه سازی شرایط تولید پروتئین هیدرولیز شده (شامل نسبت آنزیم به سوبسترا، دما و زمان) به منظور دستیابی به بالاترین خواص آنتی اکسیدانی، مینس تهیه شده از ضایعات میگوی ببری سبز (penaeus semisulcatus) پس از تعیین درصد پروتئین آن (13%، بر اساس وزن تر) با استفاده از دو پروتئاز تجاری آلکالاز و فلاورزایم بر اساس 18 تیمار تعیین شده با طرح آزمایشات سطح پاسخ برای هر آنزیم، هیدرولیز شده و با خشک کن انجم...
Betulinic acid, a pentacyclic triterpene isolated from Jujube tree (Zizyphus jujuba Mill), has been known for a wide range of biological and medicinal properties such as antibacterial, antimalarial, anti-inflammatory, antihelmintic, antinociceptive, and anticancer activities. In the study, we investigated the antiviral activity on influenza A/PR/8 virus infected A549 human lung adenocarcinoma e...
Strongyloidiasis is a common disease worldwide, has complex life cycle and infect humans percutaneously. We report case of 46-year-old woman, presented with complaints abdominal pain, distension. She was on PPI (Proton Pump Inhibitors) for recurrent gastritis. also gives history steroid intake joint pain. USG abdomen showed moderate ascites. Upper GI endoscopy diffuse erythematous gastric mucos...
Medicinal plants belongs to the oldest known health care products that have been used by mankind all over the world in the form of folklore medicines or traditional medicines or ethno medicines. The use of herbal drugs, extracts and their remedies have significantly increased throughout the world and the ‘green revolution’ in terms of herbal medicines has now achieved astonishing popularity. Th...
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