OBJECTIVE To assess the association between elevated depression symptoms or antidepressant medicine use on entry to the Diabetes Prevention Program (DPP) and during the study and the risk of developing diabetes during the study. RESEARCH DESIGN AND METHODS DPP participants (n = 3,187) in three treatment arms (intensive lifestyle [ILS], metformin [MET], and placebo [PLB]) completed the Beck De...

BACKGROUND Antidepressant drugs are among the most widely prescribed drugs in the United States; however, little is known about their use among major ethnic minority groups. METHOD Collaborative Psychiatric Epidemiology Surveys (CPES) data were analyzed to calculate nationally representative estimates of Latino and non-Latino White adults antidepressant use. SETTING The 48 coterminous Unite...

Major depressive disorder (MDD) is a chronic condition that affects one in six adults in the US during their lifetime. The current practice of antidepressant medication prescription is a trial-and-error process. Additionally, over a third of patients with MDD fail to respond to two or more antidepressant treatments. There are no valid clinical markers to personalize currently available antidepr...

with the aim of obtaining information about drug-drug interaction (ddi) between acetaminophen and some of antidepressant drugs (fluoxetine, sertraline and nortriptyline), in the present work we studied the electrochemical oxidation of acetaminophen (paracetamol) in the presence of these drugs by means of cyclic voltammetry and controlled-potential coulometry. the reaction between n-acetyl-p-ben...

asperugo procumbents l. has been used in iranian traditional medicine for the refreshing, tranquillizing and mood elevating activities. the present study was undertaken to evaluate the antidepressant and sedative-hypnotic potential of acute administration of the hydroalcoholic extract of this plant in mice.additionally, the effects of flumazenil on the hypnotic activity of the extracts were eva...

methanol extract of dried leaves of momordica charantia linn ( cucurbitaceae ) was investigated for anxiolytic, antidepressant and anti-inflammatory activities in animal models. anxiolytic activity of methanol extract of dried leaves of momordica charantia linn was tested by elevated plus maze test and the results showed a significant anxiolytic effect comparable, with diazepam in all the teste...

Background: Depression is one of the most common causes disabilities and poor quality life worldwide. One-fifth patients fail to respond antidepressant therapy. Hence, adjunct therapy urgently needed. Aim: This study aims compare effectiveness repetitive transcranial magnetic stimulation (rTMS) aerobic exercise as on activity daily living in depressed patients. Material Methods: A randomized-co...